10 Genetic associations with brain microbleeds: systematic review and meta-analyses

Introduction

The frequency of brain microbleeds (BMBs) increases with age, and with a history of hypertension, smoking and stroke (particularly intracerebral haemorrhage), but genetic associations with BMBs are less clear.

Methods

We sought all published studies of the association between any genetic polymorphism and BMBs studied in a total of >100 people. We critically appraised studies, and calculated pooled odds ratios...