N-Hydroxycinnamoyl amides of fluorinated amino acids: Synthesis, anti-tyrosinase and DPPH scavenging activities

A series of N-hydroxycinnamoyl amides of fluorinated amino acids were synthesized. Their antioxidant activity was determined using the rapid DPPH test and the activity was compared to that of non-fluorinated analogs and standard antioxidants. Results on the antiradical properties obtained by Nenadis’ method, indicate that fluorine slightly increased the radical scavenging activity of three of the studied amides. Among the tested compounds,...