Original paper
The Elg1 Replication Factor C-like Complex Functions in PCNA Unloading during DNA Replication
Abstract
The ring-shaped complex PCNA coordinates DNA replication, encircling DNA to act as a polymerase clamp and a sliding platform to recruit other replication proteins. PCNA is loaded onto DNA by replication factor C, but it has been unknown how PCNA is removed from DNA when Okazaki fragments are completed or the replication fork terminates. Here we show that the Elg1 replication factor C-like complex (Elg1-RLC) functions in PCNA unloading. Using an...
Paper Details
Title
The Elg1 Replication Factor C-like Complex Functions in PCNA Unloading during DNA Replication
Published Date
Apr 1, 2013
Journal
Volume
50
Issue
2
Pages
273 - 280
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Notes
History