Age-related changes in fibre composition of the human corpus callosum

WE found positive correlations between the number of myelinated callosal fibres > 1 μm in diameter and age in humans. The relatively abundant axons with diameters between 1 and 3 μm correlated with age only in females, while the scarce fibres > 3 μm in diameter correlated significantly with age only in males. When analysing different callosal segments, it was found that in the midbody (but not in the splenium) of females the number of fibres > 3...