Nitric oxide enhances experimental wound healing in diabetes
Abstract
Diabetes is characterized by a nitric oxide deficiency at the wound site. This study investigated whether exogenous nitric oxide supplementation with the nitric oxide donor molsidomine (N-ethoxycarbomyl-3-morpholinyl-sidnonimine) could reverse the impaired healing in diabetes.Wound healing was studied by creating a dorsal skin incision with subcutaneous polyvinyl alcohol sponge implantation in diabetic and non-diabetic rats. Half of each group...
Paper Details
Title
Nitric oxide enhances experimental wound healing in diabetes
Published Date
Dec 1, 2002
Journal
Volume
89
Issue
12
Pages
1594 - 1601
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