Original paper
Phase II study of gemcitabine and cisplatin in the treatment of patients with advanced pancreatic carcinoma
Abstract
BACKGROUND Pancreatic carcinoma is considered among the most chemoresistant of human malignancies. The most commonly used cytotoxic single agents, 5-fluorouracil and 2′-deoxy-2′,2′-difluorocytidine (gemcitabine), have objective response rates of less than 10% in large studies. Hypothesizing noncross resistance and a synergistic interaction between gemcitabine and cisplatin, early clinical studies have demonstrated significant activity with this...
Paper Details
Title
Phase II study of gemcitabine and cisplatin in the treatment of patients with advanced pancreatic carcinoma
Published Date
Jan 1, 2001
Journal
Volume
92
Issue
3
Pages
569 - 577
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Notes
History