Original paper

Oral tolerance: immune mechanisms and the generation of Th3-type TGF-beta-secreting regulatory cells

Volume: 3, Issue: 11, Pages: 947 - 954
Published: Sep 1, 2001
Abstract
Oral tolerance is a long recognized method to induce peripheral immune tolerance. Oral tolerance has been used successfully to treat animal models of autoimmune diseases and is being tested in human diseases. Low doses of oral antigen induce active suppression, whereas high doses induce clonal anergy and deletion. Oral antigen preferentially generates a Th2(IL-4/IL-10)- or a Th3(TGF-β)-type response. Th3-type cells are a unique T-cell subset...
Paper Details
Title
Oral tolerance: immune mechanisms and the generation of Th3-type TGF-beta-secreting regulatory cells
Published Date
Sep 1, 2001
Volume
3
Issue
11
Pages
947 - 954
Citation AnalysisPro
  • Scinapse’s Top 10 Citation Journals & Affiliations graph reveals the quality and authenticity of citations received by a paper.
  • Discover whether citations have been inflated due to self-citations, or if citations include institutional bias.