Review paper
Genetic modifiers of cancer risk in Lynch syndrome: a review
Abstract
The report by Aldred Scott Warthin in 1913 of a cancer family history and expanded on by Henry T. Lynch demonstrated one of the most enduring traits observed in patients with Lynch syndrome. The recognition of a variety of malignancies occurring at differing ages within a single family suggested the role of genetic variance on disease expression in an autosomal dominantly inherited genetic condition. With the identification of the genetic basis...
Paper Details
Title
Genetic modifiers of cancer risk in Lynch syndrome: a review
Published Date
Mar 8, 2013
Journal
Volume
12
Issue
2
Pages
207 - 216
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Notes
History