Original paper
Mitochondrial translocation of cofilin is an early step in apoptosis induction
Abstract
Increasing evidence suggests that movement of key proteins in or out of mitochondria during apoptosis is essential for the regulation of apoptosis. Here, we report identification of the actin-binding protein cofilin by a proteomic approach, as such a factor translocated from cytosol into mitochondria after induction of apoptosis. We found that after induction of apoptosis, cofilin was translocated to mitochondria before release of cytochrome c....
Paper Details
Title
Mitochondrial translocation of cofilin is an early step in apoptosis induction
Published Date
Nov 23, 2003
Journal
Volume
5
Issue
12
Pages
1083 - 1089
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Notes
History