Protein-bound dinitrosyl–iron complexes appearing in blood of rabbit added with a low-molecular dinitrosyl–iron complex: EPR studies

The formation of protein-bound dinitrosyl–iron complexes (DNIC) in blood plasma and packed red cell fraction has been demonstrated by the EPR method in the experiments on rabbits which were i/v injected with the low-molecular DNIC with thiosulphate. This formation was ensured by transfer of Fe+(NO+)2 moieties from low-molecular DNIC onto serum albumin or hemoglobin molecules. Protein-bound DNICs appeared immediately after low-molecular DNIC...