Sa1164 Exclusive Enteral Nutrition Optimizes Growth Outcomes Versus Corticosteroid Therapy for Pediatric Crohn's Disease

Background: The pathogenesis of IBD involves a genetically-determined dysregulation of mucosal immunity in response to environmental factors such as the gut microbiota. Multiple studies have shown the bacterial microbiota to be dysbiotic with an increase in Proteobacteria and a decrease in taxonomic richness. Serologic evidence in patients with IBD as well as mechanistic studies in murine models suggests that gut fungi, collectively referred to...