Review paper
Thyroid Hormone Regulation of Metabolism
Abstract
Thyroid hormone (TH) is required for normal development as well as regulating metabolism in the adult. The thyroid hormone receptor (TR) isoforms, α and β, are differentially expressed in tissues and have distinct roles in TH signaling. Local activation of thyroxine (T4), to the active form, triiodothyronine (T3), by 5'-deiodinase type 2 (D2) is a key mechanism of TH regulation of metabolism. D2 is expressed in the hypothalamus, white fat, brown...
Paper Details
Title
Thyroid Hormone Regulation of Metabolism
Published Date
Apr 1, 2014
Journal
Volume
94
Issue
2
Pages
355 - 382
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