Comparison of cough reflex sensitivity after an inhaled antigen challenge between actively and passively sensitized guinea pigs

Published on Sep 6, 2005in Cough
· DOI :10.1186/1745-9974-1-6
Johsuke Hara12
Estimated H-index: 12
(Kanazawa University),
Masaki Fujimura53
Estimated H-index: 53
(Kanazawa University)
+ 14 AuthorsShinji Nakao59
Estimated H-index: 59
(Kanazawa University)
Background Late asthmatic response is observed following antigen challenge in actively, but not passively, sensitized guinea pigs. Although cough reflex sensitivity is increased after antigen challenge in actively sensitized guinea pigs, it is unknown whether the antigen-induced increase in cough reflex sensitivity develops in passively sensitized animals. The aim of this study was to compare the cough reflex sensitivity to inhaled capsaicin after an inhaled antigen challenge between actively and passively sensitized guinea pigs.
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