Analysis of airway secretions in a model of sulfur dioxide induced chronic obstructive pulmonary disease (COPD)
Abstract
Hypersecretion and chronic phlegm are major symptoms of chronic obstructive pulmonary disease (COPD) but animal models of COPD with a defined functional hypersecretion have not been established so far. To identify an animal model of combined morphological signs of airway inflammation and functional hypersecretion, rats were continuously exposed to different levels of sulfur dioxide (SO2, 5 ppm, 10 ppm, 20 ppm, 40 ppm, 80 ppm) for 3 (short-term)...
Paper Details
Title
Analysis of airway secretions in a model of sulfur dioxide induced chronic obstructive pulmonary disease (COPD)
Published Date
Jun 7, 2006
Volume
1
Issue
1
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