Prospective evaluation of potential toxicity of repeated doses ofThymus vulgarisL. extracts in rats by means of clinical chemistry, histopathology and NMR-based metabonomic approach

In the field of natural extracts, research generally focuses on the study of their biological activities for food, cosmetic, or pharmacological purposes. The evaluation of their adverse effects is often overlooked. In this study, the extracts of Thymus vulgaris L. were obtained by two different extraction methods. Intraperitoneal injections of both extracts were given daily for four days to male Wistar Han rats, at two different doses for each...