Macrophage Immunomodulatory Activity of a Purified Polysaccharide Isolated fromGanoderma atrum
Abstract
The objective of this study was to evaluate the immunomodulatory effects of the purified Ganoderma atrum polysaccharide (PSG-1) on murine macrophage cell line RAW264.7. Phagocytotic assay by fluorescein isothiocyanate-dextran internalization showed that PSG-1 stimulated the phagocytosis of macrophages. G. atrum polysaccharide increased the production of NO, and the level of mRNA expression of inducible nitric oxide synthase in a dose–response...
Paper Details
Title
Macrophage Immunomodulatory Activity of a Purified Polysaccharide Isolated fromGanoderma atrum
Published Date
Apr 18, 2012
Journal
Volume
27
Issue
2
Pages
186 - 191
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