Original paper
Ethanol-related behaviors in mice lacking the sigma-1 receptor
Abstract
The Sigma-1 receptor (Sig-1R) is a chaperone protein that has been implicated in drug abuse and addiction. Multiple studies have characterized the role the Sig-1R plays in psychostimulant addiction; however, fewer studies have specifically investigated its role in alcohol addiction. We have previously shown that antagonism of the Sig-1R reduces excessive drinking and motivation to drink, whereas agonism induces binge-like drinking in rodents....
Paper Details
Title
Ethanol-related behaviors in mice lacking the sigma-1 receptor
Published Date
Jan 1, 2016
Journal
Volume
297
Pages
196 - 203
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Notes
History