Original paper
Galactomannan Downregulates the Inflammation Responses in Human Macrophages via NFκB2/p100
Abstract
We show that galactomannan, a polysaccharide consisting of a mannose backbone with galactose side groups present on the cell wall of several fungi, induces a reprogramming of the inflammatory response in human macrophages through dectin-1 receptor. The nuclear factor kappa-light-chain-enhancer of activated B cells 2 (NF κ B2)/p100 was overexpressed after galactomannan challenge. Knocking down NF κ B2/p100 using small interfering RNA (siRNA)...
Paper Details
Title
Galactomannan Downregulates the Inflammation Responses in Human Macrophages via NFκB2/p100
Published Date
Jan 1, 2015
Journal
Volume
2015
Pages
1 - 9
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Notes
History