Review paper
Error‐Prone Repair of DNA Double‐Strand Breaks
Abstract
Preserving the integrity of the DNA double helix is crucial for the maintenance of genomic stability. Therefore, DNA double-strand breaks represent a serious threat to cells. In this review, we describe the two major strategies used to repair double strand breaks: non-homologous end joining and homologous recombination, emphasizing the mutagenic aspects of each. We focus on emerging evidence that homologous recombination, long thought to be an...
Paper Details
Title
Error‐Prone Repair of DNA Double‐Strand Breaks
Published Date
Sep 28, 2015
Volume
231
Issue
1
Pages
15 - 24
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