Efficacy of epothilone B in non-small cell lung cancer cells: Role of beta-tubulin isotypes
Abstract
AACR Annual Meeting-- Apr 12-16, 2008; San Diego, CA
LB-196
Objective: Lung cancer is the most common malignancy in the world and non-small cell lung carcinoma (NSCLC) accounts for the majority of cases. Advanced NSCLC treatment often includes combination therapy with a tubulin-binding agent (TBA) and a DNA damaging agent. Prognosis for patients with advanced NSCLC remains dismal due to resistance to therapy. Epothilones are a new class of...
Paper Details
Title
Efficacy of epothilone B in non-small cell lung cancer cells: Role of beta-tubulin isotypes
Published Date
May 1, 2008
Journal
Volume
68
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