Betulinic Acid and its Derivatives as Potential Antitumor Agents
Abstract
Betulinic acid (BA) is a lupane-type pentacyclic triterpene, distributed ubiquitously throughout the plant kingdom. BA and its derivatives demonstrate multiple bioactivities, particularly an antitumor effect. This review critically describes the recent research on isolation, synthesis, and derivatization of BA and its natural analogs betulin and 23-hydroxybetulinic acid. The subsequent part of the review focuses on the current knowledge of...
Paper Details
Title
Betulinic Acid and its Derivatives as Potential Antitumor Agents
Published Date
Jun 2, 2015
Journal
Volume
35
Issue
6
Pages
1127 - 1155
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