From modeling to measurement: Developmental trends in genetic influence on adiposity in childhood

Objective Evidence of increasing heritability of BMI over childhood can seem paradoxical given longer exposure to environmental influences. Genomic data were used to provide direct evidence of developmental increases in genetic influence. Methods BMI standard deviation scores (BMI‐SDS) at ages 4 and 10 were calculated for 2,556 twin pairs in the Twins Early Development Study. Twin analyses estimated heritability of BMI‐SDS at each age and the...