Original paper
17β‐estradiol upregulates GREB1 and accelerates ovarian tumor progression in vivo
Abstract
Exogenous 17β‐estradiol (E2) accelerates the progression of ovarian cancer in the transgenic tgCAG‐LS‐TAg mouse model of the disease. We hypothesized that E2 has direct effects on ovarian cancer cells and this study was designed to determine the molecular mechanisms by which E2 accelerates ovarian tumor progression. Mouse ovarian cancer ascites (MAS) cell lines were derived from tgCAG‐LS‐TAg mice. Following intraperitoneal engraftment of two MAS...
Paper Details
Title
17β‐estradiol upregulates GREB1 and accelerates ovarian tumor progression in vivo
Published Date
Feb 25, 2014
Volume
135
Issue
5
Pages
1072 - 1084
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Notes
History