The microstructural correlates of T₁ in white matter

Purpose Several studies have shown strong correlations between myelin content and T 1 within the brain, and have even suggested that T 1 can be used to estimate myelin content. However, other micro‐anatomical features such as compartment size are known to affect longitudinal relaxation rates, similar to compartment size effects in porous media. Methods T 1 measurements were compared with measured or otherwise published axon size measurements in...