Diphenhydramine overdose and serotonin syndrome

I READ WITH INTEREST the case presented by Tanaka et al. recently published in your journal.1 They reported, for the first time, a case of central anticholinergic syndrome due to diphenhydramine overdose that shared some clinical features of serotonin syndrome. They managed their case with intravenous drip infusion of fluids and oral administration of lorazepam. The patient's abnormal vital signs, myoclonus, hyperreflexia, and mental status...