Resumen es: Objetivo: Reportar las linfadenectomia pelvicas por laparoscopia en cancer de prostata realizadas en el Hospital Central de la Policia desde Enero 2004 h...
Traditionally, patients with high-risk localized prostate cancer have been an extremely challenging group to manage due to a significant likelihood of treatment failure and prostate cancer-specific mortality (PCSM). The results of multiple large, prospective, randomized trials have demonstrated that men with high-risk features who are treated in a multimodal fashion at the time of initial diagnosis have improved overall survival. Advances in local treatments such as dose-escalated radiotherapy i...
Last. Urs E. Studer(University Hospital of Bern)H-Index: 88
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Context: Pelvic lymph node dissection (PLND) is considered the most reliable procedure for the detection of lymph node metastases in prostate cancer (PCa); however, the therapeutic benefit of PLND in PCa management is currently under debate. Objective: To systematically review the available literature concerning the role of PLND and its extent in PCa staging and outcome. All of the existing recommendations and staging tools determining the need for PLND were also assessed. Moreover, a systematic...
After reading the outstanding review by Briganti et al [1], I cannot help but think of how our care of men with prostate cancer might change if the global economic downturn continues and worsens. As an American urologist I have the added stress of change that a new presidential administration brings and the prospects of a revised American health care system [2,3]. This global economic slowdown is also playing out in the context of an aging population, an obesity epidemic, and a shortage of physi...
Nearly 30–40% of patients who undergo radical prostatectomy present with biochemical evidence of cancer recurrence and, after a mean time of 3 yr, 10–30% of them will develop clinical recurrence [1]. The diagnostic work-up in the presence of biochemical relapse should be conducted with a view to distinguishing between the probability of local failure only or of distant failure, and this is essentially guided by the kinetics of the prostatespecific antigen (PSA) values and the initial pathology. ...
Abstract Background Recent large, prospective, randomised studies have demonstrated that adjuvant radiotherapy (RT) is a safe and effective procedure for preventing disease recurrence in locally advanced prostate cancer (PCa) patients. However, no study has ever tested the role of adjuvant RT in node-positive patients after radical prostatectomy (RP). Objective We hypothesised that adjuvant RT with early hormone therapy (HT) might improve long-term outcomes of patients with PCa and nodal metasta...
Last. Kubilay Inci(Hacettepe University)H-Index: 15
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Abstract Context High-risk localised prostate cancer (PCa) is defined as significant likelihood of death from PCa or development of distant metastases. It is important to identify patients at high risk of progression who may benefit from neoadjuvant or adjuvant therapies. Objective To review definitions for high-risk localised PCa and review outcomes of different treatment modalities. Evidence acquisition Randomised and nonrandomised clinical trials addressing the characterisation of patients wi...
Abstract Background To date, there is still a paucity of data in the literature on robotic-assisted laparoscopic extended pelvic lymph node dissection (RALEPLND) in patients with prostate cancer. Objective To assess the technical feasibility of RALEPLND and to present our surgical technique. Design, setting, and participants From April 2006 to March 2008, we performed RALEPLND in 99 patients prior to robotic-assisted laparoscopic radical prostatectomy. Indications for RALEPLND were a prostate-sp...
Abstract Objective To determine the frequency of lymph node involvement in patients with clinically localized prostate adenocarcinoma who had radical prostatectomy and extended pelvic lymphadenectomy. Material and methods A prospective observational study was conducted on 137 patients with clinically localized prostate cancer of low, intermediate or high risk according to the D’Amico classification. All participants underwent radical prostatectomy plus extended pelvic lymphadenectomy in 3 refere...
Resumen Objetivo Determinar la frecuencia de compromiso ganglionar en pacientes con adenocarcinoma de prostata clinicamente localizado llevados a prostatectomia radical y linfadenectomia pelvica extendida. Material y metodos Se realizo un estudio observacional prospectivo con 137 pacientes con cancer de prostata clinicamente localizado, de riesgo bajo, intermedio y alto segun la clasificacion de D’Amico. Todos los sujetos fueron llevados a prostatectomia radical mas linfadenectomia pelvica exten...
