Annals of the New York Academy of Sciences
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#1Jennifer CableH-Index: 6
#2Edith Heard (EBI: European Bioinformatics Institute)H-Index: 78
Last. Xuhang Liu (Rockefeller University)
view all 39 authors...
The human transcriptome contains many types of noncoding RNAs, which rival the number of protein-coding species. From long noncoding RNAs (lncRNAs) that are over 200 nucleotides long to piwi-interacting RNAs (piRNAs) of only 20 nucleotides, noncoding RNAs play important roles in regulating transcription, epigenetic modifications, translation, and cell signaling. Roles for noncoding RNAs in disease mechanisms are also being uncovered, and several species have been identified as potential drug tar...
#1Olivier Roy (Université Laval)H-Index: 4
#2Jean Levasseur-Moreau (Université Laval)H-Index: 4
Last. Shirley Fecteau (Université Laval)H-Index: 34
view all 7 authors...
Patients with posttraumatic stress disorder (PTSD) display several structural brain differences when compared with healthy individuals. However, findings are particularly inconsistent for soldiers with PTSD. Here, we characterized the brain morphometry of 37 soldiers from the Canadian Armed Forces with adulthood war-related PTSD using structural magnetic resonance imaging. We assessed time since trauma, as well as PTSD, depressive, and anxiety symptoms with the Modified PTSD Symptoms Scale, Beck...
#1Lars OrbachH-Index: 3
#2Annemarie FritzH-Index: 9
#1Jennifer CableH-Index: 6
#2Joshua N. Leonard (NU: Northwestern University)H-Index: 23
Last. William C.W. Chen (MIT: Massachusetts Institute of Technology)H-Index: 17
view all 26 authors...
Synthetic biology has the potential to transform cell- and gene-based therapies for a variety of diseases. Sophisticated tools are now available for both eukaryotic and prokaryotic cells to engineer cells to selectively achieve therapeutic effects in response to one or more disease-related signals, thus sparing healthy tissue from potentially cytotoxic effects. This report summarizes the Keystone eSymposium "Synthetic Biology: At the Crossroads of Genetic Engineering and Human Therapeutics," whi...
#1Kati Tihtonen (University of Tampere)H-Index: 8
#2Päivi KorhonenH-Index: 10
Last. Outi TammelaH-Index: 26
view all 7 authors...
Insufficient calcium intake during pregnancy may lead to maternal bone resorption and lower bone density of offspring. We evaluated the impact of supplementary calcium with or without vitamin D during pregnancy on maternal and offspring bone mineral density (BMD) and teeth firmness of the offspring. Randomized controlled trials (RCTs) were searched systematically in 11 databases. Two researchers independently screened the titles and abstracts of 3555 records and the full texts of 31 records to e...
#1Isabella Starling-Alves (UW: University of Wisconsin–Madison)H-Index: 4
#2Matthew R Wronski (Rush University Medical Center)
Last. Edward M. Hubbard (UW: University of Wisconsin–Madison)H-Index: 24
view all 3 authors...
Although important for the acquisition of later math skills, fractions are notoriously difficult. Previous studies have shown that higher math anxiety (MA) is associated with lower performance in symbolic fraction tasks in adults and have suggested that MA may negatively impact the acquisition of fractions in children. However, the effects of MA on fraction skills in school-aged children remain underexplored. We, therefore, investigated the impact of MA on the performance of younger (second and ...
#1Elise Huppert (NYU: New York University)
#2Sam Parnia (NYU: New York University)H-Index: 19
Despite improvements in cardiopulmonary resuscitation (CPR), survival and neurologic recovery after cardiac arrest remain very poor because of the impact of severe ischemia and subsequent reperfusion injury. As the likelihood of survival and favorable neurologic outcome decreases with increasing severity of ischemia during CPR, developing methods to measure the magnitude of ischemia during resuscitation, particularly cerebral ischemia, is critical for improving overall outcomes. Cerebral oximetr...
#1Juan Hu (SDAU: Shandong Agricultural University)H-Index: 2
#2Baizhao Ren (SDAU: Shandong Agricultural University)H-Index: 13
Last. Jiwang Zhang (SDAU: Shandong Agricultural University)H-Index: 23
view all 6 authors...
Summer maize is frequently subjected to waterlogging damage because of increased and variable rainfall during the growing season. The application of 6-benzyladenine (6-BA) can effectively mitigate the waterlogging effects on plant growth and increase the grain yield of waterlogged summer maize. However, the mechanisms underlying this process and the involvement of 6-BA in relevant signal transduction pathways remain unclear. In this study, we explored the effects of 6-BA on waterlogged summer ma...
#1Chunmian Zhang (NENU: Northeast Normal University)H-Index: 2
#2Congnan Sun (NENU: Northeast Normal University)H-Index: 6
Last. Tinglei Jiang (NENU: Northeast Normal University)H-Index: 18
view all 6 authors...
Individual recognition via communication signals is a critical component of social behavior, and provides the basis of conflict resolution, territorial behavior, and mate choice. However, the function of chemical signals in mammalian individual recognition and conflict resolution has largely been unexplored despite olfaction being a dominant sensory modality in many mammalian species. Here, we describe behavioral tests designed to evaluate the potential role of forehead gland secretions during c...
#2Usha Govinden (UKZN : University of KwaZulu-Natal)H-Index: 10
Last. John Osei Sekyere (IU: Indiana University)
view all 3 authors...
Antimicrobial resistance (AMR) is a public health threat globally. Carbapenems are β-lactam antibiotics used as last-resort agents for treating antibiotic-resistant infections. Mobile genetic elements (MGEs) play an important role in the dissemination and expression of antimicrobial resistance genes (ARGs), including the mobilization of ARGs within and between species. The presence of MGEs around carbapenem-hydrolyzing enzymes, called carbapenemases, in bacterial isolates in Africa is concerning...
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