Psychiatry Research-neuroimaging
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#1Christopher C. Rowe (University of Melbourne)H-Index: 97
#2Natasha KrishnadasH-Index: 3
Last. Richard A A Kanaan (University of Melbourne)H-Index: 30
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Abstract null null M1 and M4 muscarinic receptor (mAChR) agonists are under development for the treatment of schizophrenia, Alzheimer's and Parkinson's disease. We performed first-in-human PET imaging of mAChR with 18F-Fluorobenzyl-Dexetimide (FDEX) in 10 healthy participants (29.4±4.3yrs). Four underwent dynamic brain scanning for 240 min, and then six underwent static brain scans at 120 and 160-min post injection of 250 MBq of FDEX. Gjedde-Patlak graphical analysis was applied to determine the...
#1Delphine Raucher-Chéné (Douglas Mental Health University Institute)H-Index: 8
#2Alexandre Obert (University of Toulouse)
Last. Arthur Kaladjian (URCA: University of Reims Champagne-Ardenne)H-Index: 8
view all 9 authors...
Abstract null null In addition to symptoms specifically related to mood dysregulation, patients with bipolar disorder (BD) show frequent alterations in formal thought organization. A disruption in semantic processing, notably in semantic inhibition, is one of the possible mechanisms that might explain this modified organization. However, to date, little is known about these mechanisms and their underlying neural substrates. This study aimed to identify the neural correlates of the semantic inhib...
#1Bárbara Duarte-Abritta (CSIC: Spanish National Research Council)H-Index: 4
#2Stella-Maris Sánchez (CSIC: Spanish National Research Council)
Last. Salvador M. GuinjoanH-Index: 19
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Abstract null null A traditional hallmark of cognitive impairment associated with late-onset Alzheimer´s disease (LOAD) is episodic memory impairment. However, early alterations have been identified in brain regions associated with executive function in asymptomatic, middle-age offspring of patients with LOAD (O-LOAD) compared to those with no family history. We hypothesized that executive function among O-LOAD would correlate with structural and amyloid brain imaging differently from those with...
#1Soobin Jo (SMC: Samsung Medical Center)
#2In Chul Baek (SMC: Samsung Medical Center)
Last. Hong Jin Jeon (SMC: Samsung Medical Center)H-Index: 33
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Abstract null null Smartphone is one of the essential items. However, it may negatively affect a user's mental health when it is overused. The study aimed to investigate associations of smartphone overuse with depression, anxiety, and the relationship with other addictive behaviors and disorders. A total of 2,509 subjects were randomly selected through a one-person-per-household method. Smartphone Overuse Screening Questionnaire (SOS-Q) and the Korean version of the Composite International Diagn...
#2Porin MakarićH-Index: 3
Last. Julian Beezhold (UEA: University of East Anglia)H-Index: 9
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Abstract null null Neurocognitive symptoms exert the most influence on treatment outcomes over the course of schizophrenia, starting from the first-episode of psychosis (FEP) onwards. Our aim was to analyze the neurocognitive status of FEP compared to healthy controls (HC), and its change after 18 months of treatment. We performed a study in a sample of 159 patients with FEP and 100 HC. We followed the patients up for 18 months after initial assessment with a battery of neurocognitive tests. We ...
#2Maeva Fortias (University of Paris)
Last. Florence Vorspan (University of Paris)H-Index: 14
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Abstract null null Psychiatric disorders, including schizophrenic spectrum disorders, are common in People Who Use Drugs (PWUD). Promoting adherence to medication among PWUD with dual diagnosis is challenging. We present the case of a treatment-disrupted patient suffering from schizophrenia with co-occuring multiple drug dependence to whom penfluridol - an oral long acting typical antipsychotic - was proposed at the Supervised Drug Consumption Room (SDCR) of Paris. Penfluridol quickly improved p...
#1Yizhu Pan (Capital Medical University)
#2Gang Wang (Capital Medical University)H-Index: 22
Last. Yuan Chen (Capital Medical University)
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Abstract null null Psychiatric emergency patients constitute a population at high risk of suicidal thoughts and behaviors (STB). However, the risk factors for STB in this population have not been clearly defined. This study aimed to explore the risk factors for STB in psychiatric emergency patients in China. A cross-sectional analysis was conducted at the emergency department of psychiatry, Anding Hospital, Capital Medical University from 2015 to 2017. The Chinese suicide risk factors scale was ...
#1Manuela Teixeira Schorr (UFRGS: Universidade Federal do Rio Grande do Sul)H-Index: 2
#2Barbara Tietbohl Martins Quadors dos Santos (UFRGS: Universidade Federal do Rio Grande do Sul)
Last. Simone Hauck (UFRGS: Universidade Federal do Rio Grande do Sul)H-Index: 9
view all 9 authors...
ABSTRACT null null Childhood trauma (CT) and parental bonding (PB) have been correlated with later antisocial personality disorder (ASPD). Aiming to better understand this complex interaction we analyzed the data from a cross-sectional study that evaluated 346 male inpatient cocaine users, using both traditional statistical analysis and machine learning (ML) approaches. Childhood Trauma Questionnaire (CTQ), Parental Bonding Instrument (PBI), and Mini International Neuropsychiatric Interview (MIN...
#1Benson S. Ku (Emory University)H-Index: 4
#2Luca Pauselli (ISMMS: Icahn School of Medicine at Mount Sinai)H-Index: 9
Last. Michael T. Compton (Columbia University)H-Index: 60
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Abstract null null Automated tools do not yet exist to measure formal thought disorder, including derailment and tangentiality, both of which can be subjectively rated using the Scale for the Assessment of Positive Symptoms after a clinical research interview. CoVec, a new automated tool, measures the semantic similarity among words averaged in a five- and ten-word window (Coherence-5 and Coherence-10, respectively). One prior report demonstrated that this tool was able to differentiate between ...
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Clinical psychology
Social psychology