Journal of Tissue Engineering and Regenerative Medicine
Papers 2248
1 page of 225 pages (2,248 results)
#1Ryosuke Nakamura (Kyoto University)H-Index: 4
#2Tatsuya Katsuno (Kyoto University)H-Index: 7
Last. Koichi Omori (Kyoto University)H-Index: 28
view all 8 authors...
Tissue-engineered tracheae have been developed to replace defective tracheae. However, the direction of ciliated cells in the regenerated epithelium remains unclear. We investigated planar polarity formed in the regenerated airway epithelium after tracheal graft implantation. We also partially resected the rat trachea and implanted a collagen scaffold. The direction of the basal foot was assessed by transmission electron microscopy. Immunofluorescence staining was performed to examine the biased...
#1Kenyu Nakayama Iwatsuki (Shinshu University)
#1Kenyu Nakayama-Iwatsuki (Shinshu University)H-Index: 1
Last. Shinichi Hochi (Shinshu University)H-Index: 30
view all 3 authors...
Dispersed single cells from pancreatic islets can configure the 3D islet-like architecture (pseudo-islets) with insulin secretion potential and controllable size through their aggregation property. The present study was designed to investigate whether cryopreservation of islets or islet cells can contribute to the efficient pseudo-islet fabrication in the rat model. In control group (CT), islet single cells were prepared by trypsin digestion of 50-400-µm o fresh control islets, and then cultured...
#1Christine Schmitt (Fraunhofer Society)
#2Florian Radetzki (MLU: Martin Luther University of Halle-Wittenberg)H-Index: 11
Last. Stefan Schwan (Fraunhofer Society)H-Index: 6
view all 12 authors...
The potential therapeutic benefit of adipose-derived stem cells (ASCs) encapsulated in an injectable hydrogel for stimulating intervertebral disc (IVD) regeneration has been assessed by a number of translational and preclinical studies. However, previous work has been primarily limited to small animal models and short-term outcomes of only a few weeks. Long-term studies in representative large animal models are crucial for translation into clinical success, especially for permanent stabilization...
#1Hilary E. Murray (Worcestershire Acute Hospitals NHS Trust)H-Index: 8
#2Ali Zafar (University Hospitals Birmingham NHS Foundation Trust)
Last. R. Downing (Worcestershire Acute Hospitals NHS Trust)H-Index: 9
view all 6 authors...
#1Arvind Manikantan Padma (University of Gothenburg)H-Index: 5
#2Ahmed Baker Alshaikh (University of Gothenburg)H-Index: 2
Last. Mats Hellström (University of Gothenburg)H-Index: 30
view all 7 authors...
Scaffolds derived from decellularized tissue possess many advantages for bioengineering applications, including for novel infertility treatments. However, the decellularization process results in allogenic-independent damage-associated molecular patterns (DAMPs). This field is poorly studied, in particular for uterus bioengineering applications. An increased knowledge concerning the immune system activation after transplantation of decellularized tissue will enable safer construct development an...
#1Michella H. Hagmeijer (UU: Utrecht University)H-Index: 3
#2Jasmijn V. Korpershoek (UU: Utrecht University)H-Index: 2
Last. Lucienne A. Vonk (UU: Utrecht University)H-Index: 16
view all 8 authors...
Meniscus regeneration could be enhanced by targeting meniscus cells and mesenchymal stromal cells (MSCs) with the right growth factors. Combining these growth factors with the Collagen Meniscus Implant (CMI®) could accelerate cell ingrowth and tissue formation in the implant and thereby improve clinical outcomes. Using a transwell migration assay and a micro-wound assay, the effect of insulin-like growth factor-1, platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF), ...
#1Minghua Hu (Changsha Medical University)
#2Xi Zhu (CSU: Central South University)
Last. Shijie Chen (CSU: Central South University)
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The disturbance of homeostasis in bone marrow-derived mesenchymal stem cell (BMSC) adipogenesis and osteogenesis could result in pathologic consequences that plays a critical role in osteoporosis pathogenesis. In the present study, we demonstrated that miR-210-3p was abnormally upregulated within the femur of osteoporosis patients and abnormally downregulated in osteogenically differentiated BMSCs. The predicted targets of candidate miRNAs were enriched in the Pluripotent stem cell differentiati...
#1Joseph S. Fernandez-Moure (Duke University)H-Index: 10
#2Jeffrey L. Van Eps (Houston Methodist Hospital)H-Index: 11
Last. Ennio TasciottiH-Index: 37
view all 10 authors...
Incisional hernia continues to be a common complication of hernia repair in spite of the development of various synthetic and bio-synthetic repair materials. Poor long-term mechanical strength, leading to high recurrence rates, has limited the use of acellular dermal matrices (ADM) in ventral hernia repair (VHR). Biologically-derived meshes have been an area of increasing interest, but these materials bring the risk of more aggressive immune response and fibrosis in addition to the mechanical fa...
#1Sachin Latiyan (IISc: Indian Institute of Science)H-Index: 3
#2Kaushik Suneet (IISc: Indian Institute of Science)H-Index: 2
Last. Shilpee Jain (IISc: Indian Institute of Science)H-Index: 8
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Although several advances have been made in the field of medicine during the last few decades, yet targeted delivery of biomolecules is still a significant challenge. Thus, the present study illustrates the fabrication of dual nature magneto-conducting Fe3 O4 -SU8 derived carbon-based Janus microbots that could deliver biomolecules efficiently inside cells. These microsystems possess dual properties, that is, the half part is magneto-conducting, and another half is only conducting for sufficing ...
#1Yiying Qi (ZJU: Zhejiang University)H-Index: 15
#2Ruofu Tang (ZJU: Zhejiang University)
Last. Wenkan Zhang (ZJU: Zhejiang University)H-Index: 3
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Objective Non-canonical Wnt5a is a particularly attractive growth factor to maintain chondrogenesis. Platelet rich plasma (PRP) is an autologous blood-derived product and a source of bioactive growth factors involved in tissue regeneration. The present study aimed to investigate the effect and inflammation reaction of Wnt5a/PRP on meniscus cells, and evaluate meniscus regeneration and osteoarthritis prevention by the application of Wnt5a/PRP gel in a rabbit model of massive meniscal defect. Desi...
Top fields of study
Biomedical engineering
Mesenchymal stem cell
Tissue engineering
Cell biology