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#1Giovanni Capovilla (UNIPD: University of Padua)H-Index: 9
#2Caterina Froiio (University of Milan)H-Index: 1
Last. Peter P. GrimmingerH-Index: 21
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Die perioperative oder neoadjuvante Therapie ist in Europa die tragende Saule der Behandlung des lokal fortgeschrittenen Magenkarzinoms, jedoch fehlen Daten fur eine mogliche Anpassung der chirurgischen Strategie in Abhangigkeit des Ansprechens auf die praoperative Behandlung. Dieses Review erfolgte auf Basis einer Recherche der relevanten aktuellen wissenschaftlichen Literatur zur neoadjuvanten oder perioperativen Behandlung des Adenokarzinoms des Magens und Implikation des Tumoransprechens auf...
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#1Tobias SchlosserH-Index: 3
Last. Ines GockelH-Index: 43
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Background null Esophageal cancer represents a complex tumor entity with an increasing proportion of adenocarcinomas. Early esophageal cancer is staged as m1-m3 depending on the depth of infiltration into the mucosa and as sm1-sm3 depending on invasion into the submucosa. The risk of lymph node metastasis is strongly correlated with the depth of invasion and increases by leaps and bounds with submucosal infiltration. null Material and methods null This review is based on publications retrieved b...
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#1Thomas Hummel (RUB: Ruhr University Bochum)H-Index: 9
#2Saskia H. Meves (RUB: Ruhr University Bochum)H-Index: 20
Last. Horst Neubauer (RUB: Ruhr University Bochum)H-Index: 16
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#1Philipp Riss (University of Vienna)
#2Katharina Scheuba (University of Vienna)
Last. Oliver Strobel (University of Vienna)
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Endocrine tumors and here in particular gastrointestinal neuroendocrine neoplasms (GEP-NET), pheochromocytomas (PC), paragangliomas (PGL) and thyroid tumors are prime examples of the importance of molecular pathology and molecular biology for the diagnostics, classification and ultimately also the (surgical) treatment of these diseases. The GEP-NETs are graded using the Ki-67 index. This determines the type of molecular imaging (DOTA/DOPA/FDG-PET/CT), the possible treatment (surgical and/or radi...
2 CitationsSource
#1Iris Tischoff (RUB: Ruhr University Bochum)H-Index: 11
#2Andrea Tannapfel (RUB: Ruhr University Bochum)H-Index: 52
Histopathologic evaluation of tumors after neoadjuvant therapy is performed by tumor regression grading (TRG) systems, which reflect the proportion of vital residual primary tumor in relation to the previous total tumor. The World Health Organization (WHO) tumor grading is replaced by TRG in tumor classification. The histopathological work-up of a tumor is based on the criteria of the TNM classification even after neoadjuvant therapy. A uniform TRG does not exist. For various tumors TRGs based o...
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#1Martin Schneider (Heidelberg University)H-Index: 23
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In Germany approximately 70,000 patients with a renal insufficiency are treated by hemodialysis. The most frequent reasons for the need for dialysis are currently diabetic nephropathy and nephrosclerosis. Due to the increasing average age and the resulting multimorbidity of dialysis patients, the difficulties of medical care have also increased. Therefore, an interdisciplinary treatment of these patients is of great importance. An important point in the treatment is the choice of vascular access...
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#1Julian Hipp (University Medical Center Freiburg)H-Index: 3
Last. Jens HoeppnerH-Index: 20
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A relevant number of patients with locally advanced esophageal squamous cell carcinoma and adenocarcinoma show a locoregional complete response of the tumor in the resected material after neoadjuvant therapy with modern chemotherapy and chemoradiation protocols. Due to a high rate of perioperative morbidity and decreased long-term quality of life following esophagectomy, the current treatment algorithm with neoadjuvant therapy and post-neoadjuvant esophagectomy on principle is critically questio...
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#1Dietmar LorenzH-Index: 19
#2Christiane BrunsH-Index: 34
Last. Heinz J BuhrH-Index: 1
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A positive association between the number of operations and postoperative hospital mortality, the so-called caseload-treatment result relation, has been confirmed many times in the literature; however, the definition of the underlying volumes is not uniform. The number of 26 resections/year/institution, which has now been established by the Federal Joint Committee as the future minimum caseload requirement, is discussed in this statement of the surgical working group upper gastrointestinal tract...
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#1Franziska Willis (University Hospital Heidelberg)H-Index: 1
#2Martin Schneider (University Hospital Heidelberg)H-Index: 23
Background null Retroperitoneal soft tissue sarcomas are rare and heterogeneous tumors with high recurrence rates that require a multimodal treatment approach and a surgical resection strategy adapted to tumor localization and histological subtype. null Objective null Based on current scientific data this article intends to provide an overview on subtype-specific features, prognostic factors and operative techniques in the surgical management of retroperitoneal soft tissue sarcomas. null Materia...
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