Endocrine Pathology
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3.17
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1275
Papers 1327
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#1Idit Tessler (HUJI: Hebrew University of Jerusalem)H-Index: 3
#2Isaac Shochat (Hillel Yaffe Medical Center)H-Index: 1
Last. Galit Avior (Hillel Yaffe Medical Center)H-Index: 2
view all 5 authors...
Despite several reports on the association between molecular profiling, aggressive histology, and clinical outcomes, the association between mutation expression and pre-operative cytology is yet to be demonstrated. Therefore, we performed a retrospective, single-center study, including all patients who underwent molecular profiling of thyroid nodules in Bethesda System for Reporting Thyroid Cytopathology (BSRTC) categories III to VI, between 2018 and 2019. Medical records were reviewed to collec...
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#1Baicheng LiH-Index: 1
#2Xinjun LiH-Index: 1
view all 8 authors...
Gastrointestinal tract neuroendocrine neoplasms (NENs) are a group of rare heterogeneous tumors with different prognoses. The 2019 WHO classification of digestive system tumors defines the classification of NENs as neuroendocrine tumors (NETs G1-G3) and neuroendocrine carcinomas (NECs). We investigated outer dense fiber of sperm tails 1 (ODF1) expression in 137 gastrointestinal tract NENs including 53 NETs G1, 29 NETs G2, 3 NETs G3, and 52 NECs. Twenty adenocarcinomas and 6 squamous cell carcino...
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#1Noriaki FukuharaH-Index: 17
#2Takeo Iwata (Niigata University of Pharmacy and Applied Life Sciences)H-Index: 19
Last. Hiroshi NishiokaH-Index: 19
view all 13 authors...
Craniopharyngioma (CP) is mainly classified into two pathological subtypes: adamantinomatous (ACP) and papillary (PCP). CTNNB1 (β-catenin) mutations are detected in ACPs, and the BRAF V600E mutation is detected in PCPs. However, genetic analysis is not always possible in general medical practice. In this study, we investigated whether immunohistochemistry could replace genetic analysis as an aid in subtype diagnosis. Here, 38 CP patients who had undergone their first tumor resection were include...
1 CitationsSource
Last. Mauro Papotti (UNITO: University of Turin)H-Index: 99
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: Pancreatic neuroendocrine tumors (PanNETs) are rare neoplasms that include even rarer variants that may pose different diagnostic problems, especially in fine needle aspiration cytology (FNAC). We describe the diagnostic clues of the amyloid-rich variant of PanNETs in endoscopic ultrasound (EUS)-guided fine needle aspiration cytology (EUS-FNAC). Three cases of PanNETs with an amyloid-rich stromal component were retrieved and retrospectively reviewed. For every case, the pancreatic lesion was i...
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#1Berna İmge Aydoğan (Ankara University)H-Index: 4
#2Adile Begum Bahcecioglu Mutlu (Ankara University)
Last. Murat Faik Erdogan (Ankara University)H-Index: 22
view all 11 authors...
The influence of chronic lymphocytic thyroiditis (CLT) on clinicopathological features and behavior of differentiated thyroid carcinoma (DTC) is still debated. In the present study, we aimed to evaluate the prognosis of DTC on the presence of CLT. A total of 649 total thyroidectomized patients (379 female, 270 male) with DTC, who had follow-up data for at least 36 months were included. Clinical, histopathological data, preoperative thyroid peroxidase antibody (TPO-ab), thyroglobulin antibody (Tg...
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#1Hanh T.T. Ngo (Ho Chi Minh City Medicine and Pharmacy University)H-Index: 5
#1Hanh Thi Tuyet NgoH-Index: 1
Last. Huy Gia Vuong (OU: University of Oklahoma)H-Index: 15
view all 7 authors...
Molecular testing has a potential to improve the management of patients with indeterminate thyroid nodules considered for surgery. This study examined the influence of molecular tests on the treatment of indeterminate nodules, particularly the differences between Western and Asian countries. Electronic databases including PubMed and Web of Science were searched for relevant articles from 2010 to March 2019. We computed meta-analysis of proportion and their 95% confidence intervals (CIs) utilizin...
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#1Sylvia L. Asa (University Hospitals of Cleveland)H-Index: 115
#2Knarik Arkun (Tufts Medical Center)H-Index: 7
Last. Ozgur Mete (UHN: University Health Network)H-Index: 34
view all 10 authors...
This morphological and immunohistochemical study demonstrates that tumors currently known as "middle ear adenomas" are truly well-differentiated epithelial neuroendocrine tumors (NETs) composed of cells comparable to normal intestinal L cells, and therefore, these tumors resemble hindgut NETs. These tumors show consistent expression of glucagon, pancreatic polypeptide, PYY, and the transcription factor SATB2, as well as generic neuroendocrine markers and keratins. The same L cell markers are exp...
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Gastric type 1 neuroendocrine tumours are considered to have low rates of proliferation and a good prognosis. We report here a patient with an aggressive well-differentiated high-grade gastric neuroendocrine tumour (gastric grade 3 NET), in a context of autoimmune gastritis. Consistent with grade 3 disease, the tumour had a Ki-67 proliferation index of 30%. Targeted next-generation sequencing identified variants of four genes, including a pathogenic ATM variant underlying the differentiation and...
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#1Baris Boyraz (Harvard University)H-Index: 5
#2Peter M. Sadow (Harvard University)H-Index: 33
Last. Ozgur Mete (UHN: University Health Network)H-Index: 34
view all 6 authors...
Tumors with papillary cribriform and morular architecture were initially considered to be variants of papillary thyroid carcinoma; however, recent observations have challenged this view. In this study, we reviewed the demographical, histopathological, and immunohistochemical features of the largest case series, consisting of 33 tumors. The age at time of pathological diagnosis ranged from 18 to 59 (mean 33) years, and all patients except one were female. Sixteen patients had multifocal and fifte...
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#1Jasna Metovic (UNITO: University of Turin)H-Index: 7
#2Isabella Castellano (UNITO: University of Turin)H-Index: 26
Last. Mauro Papotti (UNITO: University of Turin)H-Index: 99
view all 7 authors...
According to the 2019 WHO classification of breast tumors, neuroendocrine neoplasms (NENs) are classified into well-differentiated NE tumors (NET) and poorly differentiated NE carcinomas (NEC), while other breast cancers (BCs) of special and no special type with neuroendocrine (NE) features are not incorporated in this scheme anymore. We aimed to assess whether INSM1, a novel NE marker, could have a role in breast NEN subtyping. We selected 63 BCs operated from 2003 to 2018, classified as BCs wi...
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Endocrinology
Pathology
Immunohistochemistry
Carcinoma
Thyroid
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