Endocrine Pathology
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#1Tae Nakano-Tateno (U of A: University of Alberta)H-Index: 3
#2Motoyasu Satou (U of A: University of Alberta)H-Index: 2
Last. Constance L. Chik (U of A: University of Alberta)H-Index: 29
view all 8 authors...
Corticotroph carcinomas and aggressive corticotroph tumors can be resistant to conventional therapy, including surgery, radiotherapy, and medical treatment. Recent evidence suggests that temozolomide (an oral alkylating agent) administered with capecitabine (pro-drug of 5-fluorouracil) may improve progression-free survival in patients with high-risk corticotroph tumors and carcinomas. This led to the use of capecitabine and temozolomide (CAPTEM) in two patients, one with a corticotroph carcinoma...
2 CitationsSource
#1Roberta Maragliano (University of Insubria)H-Index: 9
#2Laura Libera (University of Insubria)H-Index: 5
Last. Fausto Sessa (University of Insubria)H-Index: 35
view all 12 authors...
Primary ovarian neuroendocrine neoplasms (Ov-NENs) are infrequent and mainly represented by well-differentiated forms (neuroendocrine tumors — NETs — or carcinoids). Poorly differentiated neuroendocrine carcinomas (Ov-NECs) are exceedingly rare and only few cases have been reported in the literature. A subset of Ov-NECs are admixed with non-neuroendocrine carcinomas, as it occurs in other female genital organs, as well (mostly endometrium and uterine cervix), and may be assimilated to mixed neur...
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#1Emily Bulson (University Hospitals of Cleveland)
#2Sarah Chaaban (University Hospitals of Cleveland)
Last. Sylvia L. Asa (University Hospitals of Cleveland)H-Index: 114
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#1Ja-Seong Bae (Catholic University of Korea)H-Index: 12
#2Seung-Hyun Jung (Catholic University of Korea)H-Index: 20
Last. Chan Kwon Jung (Catholic University of Korea)H-Index: 37
view all 8 authors...
Follicular-patterned tumors of the thyroid in the adult population frequently harbor RAS mutations or PAX8-PPARG rearrangement, but little is known about molecular profiles in the pediatric patients with thyroid tumors, which is rare. To identify the molecular profile of pediatric follicular-patterned tumors, we enrolled 41 pediatric patients with follicular-patterned tumors from two institutions. We did next-generation sequencing using a mutation panel targeting 49 thyroid-tumor-related genes a...
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#1Anil Aysal (Dokuz Eylül University)H-Index: 2
#2Cihan Agalar (Dokuz Eylül University)H-Index: 7
Last. Ozgul Sagol (Dokuz Eylül University)H-Index: 22
view all 7 authors...
The question of how successful we are in predicting pancreatic neuroendocrine tumors (panNET) with poor prognosis has not been fully answered yet. The aim of this study was to investigate the effects of clinicopathological features on prognosis and to determine their validity in prediction of prognosis and whether a better prognostic classification can be made. Fifty-six patients who underwent pancreatic resection for pancreatic neuroendocrine tumor were included. The associations between clinic...
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#1Yu Ah Hong (Catholic University of Korea)H-Index: 12
#2Ki Cheol Park (St Mary's Hospital)H-Index: 21
Last. Suk Young Kim (Catholic University of Korea)H-Index: 11
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Secondary hyperparathyroidism (SHPT) is characterized by excessive serum parathyroid hormone levels in response to decreasing kidney function, and tertiary hyperparathyroidism (THPT) is often the result of a long-standing SHPT. To date, several genes have been associated with the pathogenesis of primary hyperparathyroidism (PHPT). However, the molecular genetic mechanisms of uremic hyperparathyroidism (HPT) remain uncharacterized. To elucidate the differences in genetic alterations between PHPT ...
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#1Wolfgang Saeger (UHH: University of Hamburg)H-Index: 24
#2Jannik von Schöning (UHH: University of Hamburg)
Last. Ulrich J. Knappe (RUB: Ruhr University Bochum)H-Index: 12
view all 7 authors...
Between 1996 and 2020, 12,565 cases were enrolled in the German Registry of Pituitary Tumors including 10,084 PitNETs (10,067 adenomas and 19 carcinomas obtained surgically and 193 adenomas diagnosed at autopsy) as well as 69 spindle cell tumors of the neurohypophysis (64 surgical specimens and 5 autopsies). In six patients (1 post mortem and 5 surgical specimens), PitNETs as well as posterior lobe tumors were found in the specimens. Two of the PitNETs were sparsely granulated prolactin-producin...
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#1Enrico Costantino Falco (UNITO: University of Turin)H-Index: 1
#2Lorenzo DanieleH-Index: 15
Last. Mauro Papotti (UNITO: University of Turin)H-Index: 98
view all 7 authors...
Ectopic adrenal rests are a rare condition which can be found in various sites, generally in the retroperitoneum or pelvis along the path of gonadal descent. Their real prevalence is unknown. Males are more commonly affected, at least in the pediatric age. Adrenal rests are usually clinically silent and incidentally found in surgical samples, mostly in the pediatric population, and rarely in adults. With the aim of increasing knowledge and estimating the prevalence of ectopic adrenocortical tiss...
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#1Idit Tessler (HUJI: Hebrew University of Jerusalem)H-Index: 1
#2Isaac Shochat (Hillel Yaffe Medical Center)H-Index: 1
Last. Galit Avior (Hillel Yaffe Medical Center)H-Index: 2
view all 5 authors...
Despite several reports on the association between molecular profiling, aggressive histology, and clinical outcomes, the association between mutation expression and pre-operative cytology is yet to be demonstrated. Therefore, we performed a retrospective, single-center study, including all patients who underwent molecular profiling of thyroid nodules in Bethesda System for Reporting Thyroid Cytopathology (BSRTC) categories III to VI, between 2018 and 2019. Medical records were reviewed to collec...
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#1Berna İmge Aydoğan (Ankara University)H-Index: 4
#2Adile Begum Bahcecioglu Mutlu (Ankara University)
Last. Murat Faik Erdogan (Ankara University)H-Index: 22
view all 11 authors...
The influence of chronic lymphocytic thyroiditis (CLT) on clinicopathological features and behavior of differentiated thyroid carcinoma (DTC) is still debated. In the present study, we aimed to evaluate the prognosis of DTC on the presence of CLT. A total of 649 total thyroidectomized patients (379 female, 270 male) with DTC, who had follow-up data for at least 36 months were included. Clinical, histopathological data, preoperative thyroid peroxidase antibody (TPO-ab), thyroglobulin antibody (Tg...
2 CitationsSource
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Endocrinology
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Immunohistochemistry
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