BMC Ophthalmology
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#1William Mitchell (MEE: Massachusetts Eye and Ear Infirmary)
#2Edward Christopher Dee (Harvard University)H-Index: 5
Last. Leo Anthony Celi (Harvard University)H-Index: 38
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Cho et al. report deep learning model accuracy for tilted myopic disc detection in a South Korean population. Here we explore the importance of generalisability of machine learning (ML) in healthcare, and we emphasise that recurrent underrepresentation of data-poor regions may inadvertently perpetuate global health inequity.Creating meaningful ML systems is contingent on understanding how, when, and why different ML models work in different settings. While we echo the need for the diversificatio...
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#1Noa Kapelushnik (Sheba Medical Center)H-Index: 2
#2Ari Leshno (Sheba Medical Center)H-Index: 3
Last. Alon Skaat (Sheba Medical Center)H-Index: 12
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BACKGROUND Glaucoma is a leading cause of global blindness, especially preventable blindness. The increased prevalence of glaucoma has led to a growing demand for newer, safer, more rapid, and simpler treatments for the reduction of intraocular pressure (IOP). In this study, we evaluated the safety and feasibility of performing filtration glaucoma surgery with an Ab-Interno Er:YAG laser in rabbits. METHODS Nine New Zealand White rabbits age 16 weeks were studied. After subconjunctival injection ...
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#1Yusuke Mitsuoka (Osaka University)
#2Takeshi Soma (Osaka University)H-Index: 14
Last. Kohji Nishida (Osaka University)H-Index: 55
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BACKGROUND Filamentous fungi are ubiquitous in plants, water, and soil. The predominant fungi that infect the human cornea include Fusarium and Aspergillus species. The onset of fungal endophthalmitis is indolent, and typically takes weeks to months to develop after corneal infection. We report a case of Fusarium infection complicating rheumatic keratitis that acutely progressed to endophthalmitis during intravenous tocilizumab therapy. CASE PRESENTATION A 65-year-old female patient was referred...
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#1Santiago Delgado-Tirado (University of Valladolid)H-Index: 4
#2Alberto López-Miguel (University of Valladolid)H-Index: 14
Last. Rosa M. Coco-Martin (University of Valladolid)H-Index: 2
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BACKGROUND Prevalence of high myopia is continuously increasing, thus, patients affected with staphyloma are abundant worldwide. Assessment of the quality of vision in these patients is mandatory for a proper clinical counselling, specially when undergoing surgical procedures that require intraocular lenses implantation. Thus, the purpose of the study was to assess monochromatic higher order aberrations (HOAs) in highly myopic eyes with staphyloma with or without a dome-shaped macula. METHODS Pa...
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#1Si Zhang (NU: Nanjing University)
#2Chunyan Xue (NU: Nanjing University)H-Index: 4
Last. Zheng-Gao Xie (NU: Nanjing University)
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BACKGROUND Ocular toxoplasmosis caused by Toxoplasma gondii is an infectious disease which is widely distributed around the world and can present with various clinic manifestations. We are here reporting an unusual case presented with epiretinal membrane (ERM), i.e., macular pucker. CASE PRESENTATION A 16-year old male patient visited our outpatient clinic complaining of decreased vision for about 8 years in his left eye. The best-corrected visual acuity (BCVA) was 20/20 OD and 20/400 OS. There ...
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#1Sarah Alkabbani (University of Medicine and Health Sciences)
#2Lakshmanan Jeyaseelan (University of Medicine and Health Sciences)
Last. Pramod T Warhekar (University of Medicine and Health Sciences)
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BACKGROUND The prevalence of dry eye disease is increasing globally and requires the attention of healthcare professionals as it worsens patients' quality of life. No published studies on the epidemiology of dry eyes have been found in Dubai. PURPOSE To describe the epidemiology, prevalence, severity, and associated factors of dry eyes in Dubai, United Arab Emirates, in 2019. METHODS This was an analytical, cross-sectional, survey-based study. An online survey was distributed by email to Mohamme...
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#2Xiaobing Yu (Peking Union Medical College)H-Index: 3
Last. Lixin Guo (Peking Union Medical College)
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BACKGROUND To investigate the changes in retinal nerve fiber layer thickness and macular blood flow density during the preclinical stage of diabetic retinopathy and their relationship with blood glucose. METHODS In this cross-sectional study, 97 diabetic patients (total of 188 eyes; 144 eyes in no diabetic retinopathy group, 44 eyes in mild diabetic non-proliferative retinopathy group) and 35 healthy people (70 eyes) were enrolled, All the subjects were divided into different groups based on the...
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#1Xianggui Wang (CSU: Central South University)
#2Xuezhi Zhou (CSU: Central South University)
Last. Huizhuo Xu (CSU: Central South University)
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BACKGROUND To investigate the feasibility and efficacy of posterior pole retinotomy to treat recurrent macular hole retinal detachment (MHRD) in highly myopic patients. METHODS We performed a retrospective study and reviewed the medical records in our hospital between January 1, 2016 and December 31, 2018. Highly myopic patients who received posterior pole retinotomy with silicone oil tamponade for their recurrent MHRD after pars plana vitrectomy were included in the analysis. Postoperative reti...
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#1Yun-Qin Li (Yunnan University)
#2Junliang Jiang (Yunnan University)
Last. Yue Zou (Yunnan University)
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Background Insulin positively correlates with the length of the eye axis and is increased in the vitreous and serum of patients with pathological myopia (PM). How insulin influences the physiological process of retinal pigment epithelial (RPE) cells in PM remains unclear. This study aimed to explore the effect of insulin on the ultrastructure and function of RPE cells and the role of PI3K/AKT/mTOR signaling involved in the development of PM. Methods The ARPE-19 cells were treated with different ...
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#1Ahmad S Rehmani (UTMB: University of Texas Medical Branch)
#2Touka Banaee (UTMB: University of Texas Medical Branch)H-Index: 1
Last. Fuad Makkouk (UTMB: University of Texas Medical Branch)H-Index: 1
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BACKGROUND Report a rare case of retinal capillary macroaneurysm with associated subretinal fluid. CASE PRESENTATION A 71-year-old male underwent full ophthalmic examination including Optical Coherence Tomography (OCT), Fluorescein Angiography (FA). Fundus examination showed moderate non-proliferative diabetic retinopathy of both eyes with scattered microaneurysms. On initial visit, FA displayed a hyperfluorescent lesion with leakage on late frames in the left eye. OCT revealed the lesion to be ...
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Top fields of study
Ophthalmology
Surgery
Visual acuity
Glaucoma
Intraocular pressure
Diabetes mellitus
Medicine