International Journal of Hematology
Papers 5390
1 page of 539 pages (5,390 results)
#1Ivetta Danylesko (Sheba Medical Center)H-Index: 6
#2Rina Sareli (Sheba Medical Center)
Last. Arnon Nagler (Sheba Medical Center)H-Index: 118
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Autologous stem cell transplantation (ASCT) is a standard of care in newly-diagnosed multiple myeloma (MM) patients. Several studies before the introduction of novel therapies in MM, demonstrated a pegylated G-CSF to be successful in mobilizing peripheral blood stem cells (PBSCs). Lipegfilgrastim is a novel long-acting G-CSF that is produced by the conjugation of a single 20-kDa polyethelene glycol to the natural O-glycosylation site of G-CSF. Twenty-four MM patients were included for PBSCs mobi...
#1Ashley Carroll Bizzell (Baylor University)
#2Mariam Katie Mousavi (Baylor University)
Last. Ellen Yin (Baylor University)
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Fixed-dose prothrombin complex concentrates (PCCs) for the reversal of vitamin K antagonists may decrease the incidence of thromboembolic events, treatment costs, and treatment delays. However, the ideal fixed dose is unknown, with some studies showing inadequate reversal with suboptimal dosing or in patients with a higher international normalized ratio (INR) or weight. This indicates a need for a modified fixed-dose strategy that considers weight and INR. This study was a retrospective chart re...
#1Kangkang Lv (Soochow University (Suzhou))H-Index: 1
#2Chengsen Cai (Soochow University (Suzhou))H-Index: 1
Last. Xiaowen Tang (Soochow University (Suzhou))H-Index: 16
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Although defined as a lymphoid surface marker, CD7 is aberrantly expressed on a subtype of acute myeloid leukemia cells and appears to be associated with an inferior response to chemotherapy. Allogeneic hematopoietic cell transplantation (allo-HCT) is a potentially curative modality but no data has been reported in CD7-positive AML patients. We performed a retrospective analysis involving 141 AML patients who underwent allo-HCT in first morphological complete remission (CR1). The results showed ...
#1Min Zhan (Boston Children's Hospital)H-Index: 1
#2Zebin Chen (Boston Children's Hospital)H-Index: 1
Last. Feiqiu Wen (Boston Children's Hospital)H-Index: 1
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This study aimed to establish a predictive model to identify children with hematologic malignancy at high risk for delayed clearance of high-dose methotrexate (HD-MTX) based on machine learning. A total of 205 patients were recruited. Five variables (hematocrit, risk classification, dose, SLC19A1 rs2838958, sex) and three variables (SLC19A1 rs2838958, sex, dose) were statistically significant in univariable analysis and, separately, multivariate logistic regression. The data was randomly split i...
#1Akinao Okamoto (Fujita Health University)H-Index: 9
#2Yoshinobu Kanda (Jichi Medical University)H-Index: 38
Last. Kazuo Tamura (Fukuoka University)H-Index: 50
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Objectives null Bloodstream infection (BSI) is a frequent complication observed in patients with febrile neutropenia (FN). BSI risk factors and incidence vary depending on chemotherapy types and prophylactic antimicrobial agents. We clarified these issues by post-hoc analysis of a prospective clinical trial cohort for severe FN in hematological malignancy. null Methods null We performed an intention-to-treat analysis of 413 high-risk patients and 1272 blood culture sets. null Results null Overal...
#1Shunichiro Yasuda (Tokyo Medical and Dental University)H-Index: 4
#2Satoru Aoyama (Tokyo Medical and Dental University)H-Index: 3
Last. Noriko DokiH-Index: 13
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Ruxolitinib (RUX), a JAK1/2-inhibitor, is effective for myeloproliferative neoplasm (MPN) with both JAK2V617 F and calreticulin (CALR) mutations. However, many MPN patients develop resistance to RUX. Although mechanisms of RUX-resistance in cells with JAK2V617 F have already been characterized, those in cells with CALR mutations remain to be elucidated. In this study, we established RUX-resistant human cell lines with CALR mutations and characterized mechanisms of RUX-resistance. Here, we found ...
#1Yoshitaka Yamasaki (Kurume University)H-Index: 2
#2Satoshi Morishige (Kurume University)H-Index: 7
Last. Fumihiko Mouri (Kurume University)H-Index: 4
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Lymphomatoid granulomatosis (LYG) is a rare Epstein-Barr virus (EBV)-driven B-cell lymphoproliferative disease affecting mainly extranodal sites such as the lung, central nervous system (CNS), skin, kidney, and liver. We report a case of low-grade LYG involving the CNS that was successfully treated with interferon alpha (IFNα). A 69-year-old woman developed necrotic erythema of the skin and was initially diagnosed with pyoderma gangrenosum based on skin biopsy. She showed a limited response to p...
Patients with cancer are considered at high risk of acquiring coronavirus disease (COVID-19). To identify patients who are likely to be diagnosed with severe COVID-19, we analyzed the risk factors for mortality in patients admitted to the hematology department at our institute. The mortality rate of all patients was as high as 62% (21 of the 34 patients), and most of these patients had malignant malignancies. Patients before an achievement of remission had a 10.8-fold higher risk of death than t...
#1Huimin Jiang (Anhui Medical University)
#2Liangquan Geng (USTC: University of Science and Technology of China)H-Index: 11
Last. Guangyu Sun (USTC: University of Science and Technology of China)H-Index: 2
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Objective null To explore the incidence and risk factors of late-onset hemorrhagic cystitis (LOHC) in patients undergoing single umbilical cord blood transplantation for hematological malignancies. null Methods null Clinical data from 234 patients who consecutively underwent single UCBT using a myeloablative conditioning regimen without antithymocyte globulin in our center were retrospectively analyzed. null Results null In total, 64 (27.4%) patients developed LOHC with a median onset time of 40...
Top fields of study
Bone marrow
Diabetes mellitus