Journal of Gastroenterology
IF
6.13
Papers
4621
Papers 4717
1 page of 472 pages (4,717 results)
Newest
#1Shiko Kuribayashi (Gunma University)H-Index: 7
#2Junichi AkiyamaH-Index: 18
Last. Toshio Uraoka (Gunma University)H-Index: 35
view all 13 authors...
Background A new automated diagnostic program for high-resolution esophageal manometry (HREM) has been developed. This diagnostic program could detect locations of landmarks and could make final diagnoses automatically. However, the accuracy of the program is not known. The aim of this study was to evaluate the accuracy of the automated diagnostic program for HREM. Methods A total of 445 studies were enrolled. An HREM system (Starlet®) was used, and esophageal motility was diagnosed using the Ch...
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#1Takuji OkusakaH-Index: 59
#2Kenji IkedaH-Index: 58
Last. Hiromitsu KumadaH-Index: 70
view all 20 authors...
BACKGROUND REFLECT was an open-label, phase 3 study comparing the efficacy and safety of lenvatinib versus sorafenib in patients with unresectable hepatocellular carcinoma (uHCC). Based on phase 2 study (Study 202) results, body weight-based dosing for lenvatinib was used in REFLECT to minimize dose disruptions and modifications needed to address dose-related adverse events. This post hoc analysis of REFLECT data assessed lenvatinib efficacy and safety by body weight group. METHODS The study ran...
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#1Shinichiro Shinzaki (Osaka University)H-Index: 22
#2Katsuyoshi Matsuoka (Toho University)H-Index: 28
Last. Takayuki Matsumoto (Iwate Medical University)H-Index: 52
view all 23 authors...
Background This multicenter prospective study (UMIN000019958) aimed to evaluate the usefulness of serum leucin-rich alpha-2 glycoprotein (LRG) levels in monitoring disease activity in inflammatory bowel disease (IBD). Methods Patients with moderate-to-severe IBD initiated on adalimumab therapy were enrolled herein. Serum LRG, C-reactive protein (CRP), and fecal calprotectin (fCal) levels were measured at week 0, 12, 24, and 52. Colonoscopy was performed at week 0, 12, and 52 for ulcerative colit...
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#1M Romańczyk (Medical University of Silesia)
#2Bartosz Ostrowski (Medical University of Silesia)
Last. Marek Hartleb (Medical University of Silesia)H-Index: 17
view all 13 authors...
BACKGROUND Esophagogastroduodenoscopy (EGD) is commonly used diagnostic method with no widely accepted quality measure. We assessed quality indicator-composite detection rate (CDR)-consisting of detection of at least one of the following: cervical inlet patch, gastric polyp and post-ulcer duodenal bulb deformation. The aim of the study was to validate CDR according to detection rate of upper gastrointestinal neoplasms (UGN). METHODS It was a multicenter, prospective, observational study conducte...
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#1Yoshifumi Shimada (Niigata University)H-Index: 13
#2Shujiro Okuda (Niigata University)H-Index: 28
Last. Toshifumi Wakai (Niigata University)H-Index: 38
view all 16 authors...
BACKGROUND Tumor mutational burden-high (TMB-H), which is detected with gene panel testing, is a promising biomarker for immune checkpoint inhibitors (ICIs) in colorectal cancer (CRC). However, in clinical practice, not every patient is tested for TMB-H using gene panel testing. We aimed to identify the histopathological characteristics of TMB-H CRC for efficient selection of patients who should undergo gene panel testing. Moreover, we attempted to develop a convolutional neural network (CNN)-ba...
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#1Sayoko Kinowaki (Hokkaido University)
#2Yuichi Shimizu (Hokkaido University)H-Index: 25
Last. Naoya Sakamoto (Hokkaido University)H-Index: 48
view all 12 authors...
BACKGROUND AND AIM Endoscopic balloon dilation (EBD) is effective for esophageal stenosis caused by ESD. However, an efficient EBD method has not been established. We, therefore, conducted EBD experiments on porcine esophageal stenosis models. METHODS Study 1: in dilation models (day 22 after ESD), the thickness of the outer muscle layer (as an index of the extension effect) and the area of muscle fiber bundle necrosis in the inner muscle layer (as an index of thermal damage) were evaluated. Stu...
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#1Waku Hatta (Tohoku University)H-Index: 12
#2Tomoyuki Koike (Tohoku University)H-Index: 26
Last. Atsushi Masamune (Tohoku University)H-Index: 53
view all 31 authors...
Background We aimed to elucidate the risk of metastatic recurrence after endoscopic resection (ER) without additional treatment for esophageal squamous cell carcinomas (ESCCs) with tumor invasion into the muscularis mucosa (pT1a-MM) or submucosa (T1b-SM). Methods We retrospectively enrolled patients with pT1a-MM/pT1b-SM ESCC after ER at 21 institutions in Japan between 2006 and 2017. We compared metastatic recurrence between patients with and without additional treatment, stratified into categor...
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#1Hiroko Abe (Tohoku University)H-Index: 2
#2Waku Hatta (Tohoku University)H-Index: 12
Last. Atsushi Masamune (Tohoku University)H-Index: 53
view all 17 authors...
Background Delayed bleeding is the major adverse event in upper gastrointestinal endoscopic treatment (UGET). We aimed to investigate the efficacy of vonoprazan, which is the novel strong antisecretory agent, to reduce the risk for delayed bleeding in comparison with proton pump inhibitors (PPIs) in UGET. Methods This retrospective population-based cohort study used the Diagnosis Procedure Combination database in Japan. We included patients on vonoprazan or PPI in UGET between 2014 and 2019. The...
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#1Yuki Hayashi (Sapporo Medical University)H-Index: 1
#2Kohei Wagatsuma (Sapporo Medical University)H-Index: 5
Last. Hiroshi Nakase (Sapporo Medical University)H-Index: 37
view all 9 authors...
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#1Toshikazu Kobayashi (YU: Yamagata University)H-Index: 1
#2Yuko Omori (Tohoku University)H-Index: 5
Last. Toru Furukawa (Tohoku University)H-Index: 44
view all 10 authors...
Background Intraductal papillary mucinous neoplasm (IPMN) of the pancreas is categorized into four distinct types: the gastric, intestinal, pancreatobiliary, and oncocytic. Each type is associated with specific clinicopathological features. We aimed to uncover the molecular mechanisms underlying the development of these types of IPMN. Methods We obtained 103 lesions of various types, including 49 gastric, 26 intestinal, 22 pancreatobiliary, and 6 oncocytic lesions, from 43 IPMNs, including 36 wi...
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