Journal of Gastroenterology
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6.13
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4621
Papers 4739
1 page of 474 pages (4,739 results)
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#1Katsuyoshi Ando (Asahikawa Medical University)H-Index: 7
#2Mikihiro Fujiya (Asahikawa Medical University)H-Index: 28
Last. Masakazu Nagahori (Tokyo Medical and Dental University)H-Index: 18
view all 34 authors...
The mortality and risk factors of severe disease and death due to arterial and venous thromboembolism (ATE and VTE, respectively) in patients with inflammatory bowel disease (IBD) remain unclear, especially in Asia. This study aimed to reveal the mortality and risk factors of TE in IBD patients in Japan. In the primary surveillance, responses to questionnaires regarding the number of cases of severe TE and TE-associated death in IBD patients in a span of over the past 10 years were obtained from...
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#1Masato Yoneda (YCU: Yokohama City University)H-Index: 56
Last. Shingo Kato (YCU: Yokohama City University)H-Index: 21
view all 13 authors...
Nonalcoholic fatty liver disease (NAFLD) and metabolic dysfunction associated fatty liver disease (MAFLD) have important associations with cardiovascular disease (CVD). The main objective of this study was to compare the frequency of incidence rate of CVD in the NAFLD or MAFLD patients utilizing a large claims database. Using the JMDC database from April 2013 to March 2019, we retrospectively analyzed data for 1,542,688 and 2,452,949 people to estimate the relationship between CVD and NAFLD, MAF...
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#1Daiki YamashigeH-Index: 1
#2Tetsuya HosakaH-Index: 55
Last. Satoshi SaitohH-Index: 61
view all 14 authors...
Few studies have demonstrated the potency of tenofovir alafenamide (TAF) in patients with poor response to other nucleos(t)ide analogs (NAs). We conducted a retrospective study comprising consecutive 40 patients exhibiting a poor response to other NAs, who subsequently received TAF-containing regimens. The primary outcome was the prevalence of virological response (VR) at each time and maintained virological response (MVR) under TAF-containing regimens until week 96. In the entire cohort, the pr...
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#1Miki Miura (Kyorin University)H-Index: 4
#2Hirotaka ShimizuH-Index: 6
Last. Itaru IwamaH-Index: 3
view all 13 authors...
The Epstein–Barr virus (EBV) infection status in patients with inflammatory bowel disease (IBD), particularly those using thiopurines, may be associated with the risk of lymphoproliferative disorder and hemophagocytic lymphohistiocytosis. This was the first multicenter survey of EBV infection in Japanese patients with IBD. Factors related to the EBV infection status were also investigated. Five tertiary institutions in Japan participated in this study to examine pediatric and adult patients with...
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#7Masafumi Ikeda (International University of Health and Welfare)H-Index: 3
Neuroendocrine neoplasms (NENs) are rare neoplasms that occur in various organs and present with diverse clinical manifestations. Pathological classification is important in the diagnosis of NENs. Treatment strategies must be selected according to the status of differentiation and malignancy by accurately determining whether the neoplasm is functioning or nonfunctioning, degree of disease progression, and presence of metastasis. The newly revised Clinical Practice Guidelines for Gastroenteropanc...
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#1Vincent Quoc-Huy Trinh (VUMC: Vanderbilt University Medical Center)H-Index: 1
#2Nooshin K. Dashti (VUMC: Vanderbilt University Medical Center)
Last. Justin Merrill Marken Cates (VUMC: Vanderbilt University Medical Center)
view all 3 authors...
Standard risk assessment algorithms for gastrointestinal stromal tumor (GIST) are based on anatomic and histopathological variables with arbitrarily defined subcategories. Our goal was to improve risk assessment for GIST through retrospective analysis of patient data. The National Cancer Database (NCDB) was queried for patients with GIST; the final cohort consisted of 19,030 cases. Main outcomes were metastasis at presentation and overall survival. A test dataset was used to reevaluate risk stra...
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#1Tatsunori Hanai (Gidai: Gifu University)H-Index: 15
#2Kayoko Nishimura (Gidai: Gifu University)H-Index: 5
Last. Masahito Shimizu (Gidai: Gifu University)H-Index: 57
view all 9 authors...
The JSGE/JSH guidelines for the management of patients with liver cirrhosis revised in 2020 recommends new strategies for nutritional assessment and intervention, although their usefulness in daily clinical practice is unclear. A total of 769 patients with cirrhosis were classified into low-, intermediate-, and high-risk groups according to hypoalbuminemia and sarcopenia, the criteria established for initiating the nutritional therapy algorithm in the guidelines. The association between these gr...
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Background null Recent studies highlighted the clinicopathological heterogeneity of non-ampullary duodenal adenomas and adenocarcinomas, but the detailed process of the malignant transformation remains unclear. null Methods null We analyzed 144 adenomas and 54 adenocarcinomas of the non-ampullary duodenum for immunohistochemical phenotypes, genetic alterations, and mismatch repair (MMR) status to probe their histogenetic relationship. null Results null The median ages of patients with adenoma an...
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#1Jessica El Halabi (Harvard University)
#2Nathan Palmer (Harvard University)H-Index: 18
Last. Maha R. Farhat (Harvard University)H-Index: 18
view all 5 authors...
Clostridioides difficile infection (CDI) may be rising in severity in the US over the past decade and its treatment landscape is changing given the recent adoption of fecal microbiota transplantation (FMT) We built a retrospective observational cohort using a database of a national care-plan containing medical claims of over 50 million individuals between 2008 and 2019. We used International Classification of Disease (ICD) and prescription data to identify patients with CDI. We estimated trends ...
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#1Takahiko Toyonaga (Kitasato University)H-Index: 11
#2Taku Kobayashi (Kitasato University)H-Index: 71
Last. Ryo Ozaki (Kitasato University)H-Index: 4
view all 15 authors...
BACKGROUND AND AIMS Polymorphisms in the nucleotide diphosphate-linked moiety X-type motif 15 (NUDT15) gene are associated with thiopurine-induced leukopenia in patients with inflammatory bowel disease (IBD). NUDT15-associated subcellular thiopurine metabolism has not been investigated in primary lymphocytes. We hypothesized that NUDT15 mutation increases DNA-incorporated deoxythioguanosine (dTG) and induces apoptosis in lymphocytes. METHODS DNA-incorporated dTG in peripheral blood mononuclear c...
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