Thoracic Cancer
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#1Yoichi Ohtaki (Gunma University)H-Index: 14
#2Kyoichi Kaira (Saitama Medical University)H-Index: 46
Last. Takayuki KosakaH-Index: 25
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OBJECTIVES Various drug-sensitivity markers have been reported to be associated with tumor progression and chemotherapy resistance. Detailed expression profiles of sensitivity markers for cytotoxic chemotherapy in pulmonary large cell neuroendocrine carcinoma (LCNEC) remain unclear. Herein, we aimed to clarify the correlation between the expression of drug-sensitivity markers and clinicopathological features, prognostic impact, and status of tumor immunity in patients with LCNEC. METHODS We retr...
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#2Diangeng LiH-Index: 5
Last. Meiling Jin (Chinese PLA General Hospital)
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BACKGROUND GPRIN1 may be a novel tumor regulator, but its role and mechanism in tumors are still unclear. METHODS First, a pan-cancer correlation analysis was conducted on the expression and prognosis of GPRIN1 based on the data downloaded from The Cancer Genome Atlas (TCGA) database. Second, the Starbase database was used to predict the upstream miRNAs and lncRNAs of GPRIN1, and the expression analysis, survival analysis, and correlation analysis were performed to screen the microRNA (miRNAs)/l...
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#1Sally Ziatabar (WMC: Westchester Medical Center)
#2Ester Sherman (WMC: Westchester Medical Center)
Last. Oleg Epelbaum (WMC: Westchester Medical Center)H-Index: 6
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#1Ana Emília Goulart Lemos (FIOCRUZ: Oswaldo Cruz Foundation)H-Index: 2
#2Gabriela Ribeiro Silva (Federal Fluminense University)
Last. Aline R. Matos (WHO: World Health Organization)H-Index: 3
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Several studies have highlighted that cancer patients tend to be more susceptible to develop severe infection and to die from COVID-19. Certain medical conditions such as immunosuppression, presence of comorbidities, and underlying pulmonary damage are possible determinants of disease severity, especially in lung cancer patients. While recent studies have shown that lung cancer is one of the most prevalent tumor types among COVID-19 cancer patients, we still have an incomplete view of how data f...
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#1Jun Du (Peking Union Medical College)
#2Yundi Zhang (Peking Union Medical College)
Last. Zhijie Wang (Peking Union Medical College)H-Index: 23
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BACKGROUND With the improvement of therapeutic strategies from cytotoxic chemotherapy to immunotherapy, the possibility of achieving timely intervention for lung cancer has dramatically increased. This study aimed to systematically evaluate the reporting quality of randomized controlled trials (RCT) on immunotherapy in lung cancer. METHODS The RCTs evaluating the efficacy of immunotherapy in lung cancer published up to 2021 were searched and collected from PUBMED and EMBASE by two investigators....
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#1Aiqin FuH-Index: 1
#2Ze YuH-Index: 1
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Breast cancer (BC) is the most commonly occurring malignancy in women. This study aimed to investigate the functions of the long noncoding RNA ZBED3-AS1 (ZBED3-AS1) in BC and its molecular mechanisms. qRT-PCR was conducted to access the expression of ZBED3-AS1, microRNA-513a-5p (miR-513a-5p), and Kruppel like factor 6 (KLF6) in BC. Additionally, BC cell viability and proliferative capacity were measured by MTT and 5-Ethynyl-20-deoxyuridine (EdU) assays. A transwell assay was used for evaluating ...
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#1Sheng Xu (Peking Union Medical College)H-Index: 2
#2Zhixin Bie (Peking Union Medical College)H-Index: 2
Last. Xiaoguang Li (Peking Union Medical College)H-Index: 7
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Background null The aim of the study was to explore the outcomes of computed tomography-guided microwave ablation (MWA) in non-small cell lung cancer (NSCLC) patients with adjacent lobe invasion (ALI), and to compare the outcomes of ALI-NSCLC and non-ALI NSCLC patients after MWA. null Methods null A total of 319 NSCLC patients and 366 tumors treated with MWA were included in the study, comprising 34 ALI-NSCLC patients and 285 non-ALI NSCLC patients. Complications, local recurrence rates, progres...
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#1Hao-Hua Zhu (Peking Union Medical College)H-Index: 1
#2Yutao Liu (Peking Union Medical College)H-Index: 5
Last. Xingsheng Hu (Peking Union Medical College)H-Index: 8
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BACKGROUND The aim of the study was to define the clinical significance of circulating tumor cells (CTCs)/circulating tumor endothelial cells (CTECs) and their subtypes in small cell lung cancer (SCLC) patients. METHODS CTCs/CTECs and their subtypes were determined using SE-iFISH technology in 33 SCLC patients before initial treatment (B1), after two cycles of chemotherapy (B2), at the completion of chemotherapy (B3), and disease progression (B4). The correlations with clinical characteristics, ...
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#2Adnan Bakir (University of Southampton)
Last. Khalid AmerH-Index: 9
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Background null Paraspinal tumors are rare neoplasms arising from neurogenic elements of the posterior mediastinum and surgical resection can be challenging. Here, we demonstrate feasibility and outcomes from the first European case series of combined laminectomy and video-assisted thoracoscopic surgery (VATS) resection of thoracic neurogenic dumbbell tumors. null Methods null A retrospective review of all combined thoracic dumbbell tumor resections performed at our institution between March 201...
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#1Jinye Mi (University of South China)
Last. Yongchang Zhang (University of South China)H-Index: 7
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