medRxiv
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#1Natalia Lewis (University of Bristol)H-Index: 6
#2Muzrif Munas (University of Peradeniya)
Last. Loraine J. Bacchus (University of London)H-Index: 21
view all 14 authors...
Objectives. To synthesise evidence on the effectiveness, cost-effectiveness, and barriers to responding to violence against women (VAW) in sexual and reproductive health (SRH) services in low- and middle-income countries (LMICs). Design. Mixed-methods systematic review. Data sources. Medline, Embase, Psycinfo, Cochrane, Cinahl, IMEMR, Web of Science, Popline, Lilacs, WHO RHL, ClinicalTrials.gov, Google, Google Scholar, websites of key organisations through December 2019. Eligibility criteria. St...
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#2Ryan Luginbuhl (Mitre)
Last. Richard A. ParkerH-Index: 40
view all 3 authors...
Both clinical trials and studies leveraging real-world data have repeatedly confirmed the three COVID-19 vaccines authorized for use by the Food and Drug Administration are safe and effective at preventing infection, hospitalization, and death due to COVID-19 and a recent observational study of self-reported symptoms provides support that vaccination may also reduce the probability of developing long-COVID. As part of a federated research study with the COVID-19 Patient Recovery Alliance, Arcadi...
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Last. Mohamed Hadi Mohamed Abdelhamid (CDC: Centers for Disease Control and Prevention)
view all 6 authors...
Aims Coronary artery disease (CAD) is the leading cause of death worldwide in both men and women. Accordingly, we retrospectively reviewed the effects of various risk factors on coronary angiographic outcomes. Methods and Results Data were collected from the catheter lab through Tripoli university hospital records, whereas the team reviewed clinical data and coronary artery diagrams for one year from 01/04/2019 to 31/03/2020. In our study, the total number of cases was 666; 401 male and 265 fema...
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#1James R. Occean (USF: University of South Florida)H-Index: 1
#2Agaz Hussain Wani (USF: University of South Florida)H-Index: 3
Last. Monica Uddin (USF: University of South Florida)H-Index: 49
view all 9 authors...
BackgroundThe mechanisms through which exposure to differing trauma types become biologically embedded to shape the risk for subsequent post-traumatic stress disorder (PTSD) is unclear. DNA methylation (5-mC), particularly in stress-relevant genes, may play a role in this relationship. null MethodsWe conducted path analysis using generalized structural equation modeling to investigate whether blood-derived 5-mC in Nuclear Factor of Activated T Cells 1 (NFATC1) mediated the prospective associatio...
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#2Yongzhen Chen (WUSTL: Washington University in St. Louis)
Last. Shu Jiang (WUSTL: Washington University in St. Louis)H-Index: 2
view all 6 authors...
This systematic review aimed to assess the methods used to classify mammographic breast parenchymal features in relation to prediction of future breast cancer including the time from mammogram to diagnosis of breast cancer, and methods for the identification of texture features and selection of features for inclusion in analysis. The databases including Medline (Ovid) 1946-, Embase.com 1947-, CINAHL Plus 1937-, Scopus 1823-, Cochrane Library (including CENTRAL), and Clinicaltrials.gov. were sear...
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#1Amy Ferguson (University of Edinburgh)H-Index: 1
#2Sophie Thrippleton (University of Edinburgh)H-Index: 1
Last. Kristiina Rannikmäe (University of Edinburgh)H-Index: 16
view all 11 authors...
Based on previous case reports and disease-based cohorts, a minority of patients with cerebral small vessel disease (cSVD) have a monogenic cause, with many also manifesting extra-cerebral phenotypes. We investigated the frequency, penetrance, and phenotype associations of rare variants in cSVD genes in UK Biobank (UKB), a large population-based study. null We used a systematic review of previous literature and ClinVar to identify putative pathogenic rare variants in CTSA, TREX1, HTRA1, COL4A1/2...
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#1von Saint Andre-von Arnim (UW: University of Washington)
#3Kumar (Seattle Children's Research Institute)
Last. Walson
view all 9 authors...
Introduction: Pediatric mortality remains unacceptably high in many low-resource settings, with inpatient deaths often associated with delayed recognition of clinical deterioration. The Family-Assisted Severe Febrile Illness ThERapy (FASTER) tool has been developed for caregivers to assist in monitoring their hospitalized children and alert clinicians. While utilization of the tool is feasible, the impact on outcomes in low-resource settings has not been studied. Methods: Randomized controlled p...
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#1Antonello Maruotti (LUMSA: Libera Università Maria SS. Assunta)H-Index: 26
#2Giovanna Jona-Lasinio (Sapienza University of Rome)H-Index: 9
Last. Alessio Farcomeni (University of Rome Tor Vergata)H-Index: 52
view all 6 authors...
We compare the expected all-cause mortality with the observed one for different age classes during the pandemic in Lombardy, which was the epicenter of the epidemic in Italy and still is the region most affected by the pandemic. A generalized linear mixed model is introduced to model weekly mortality from 2011 to 2019, taking into account seasonal patterns and year-specific trends. Based on the 2019 year-specific conditional best linear unbiased predictions, a significant excess of mortality is ...
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#1Urszula Radzikowska (Swiss Institute of Allergy and Asthma Research)H-Index: 7
#2Andrzej Eljaszewicz (Swiss Institute of Allergy and Asthma Research)H-Index: 14
Last. Milena Sokolowska (Swiss Institute of Allergy and Asthma Research)H-Index: 31
view all 24 authors...
Rhinoviruses (RV) and inhaled allergens, such as house dust mite (HDM) are the major agents responsible for asthma onset, its life-threatening exacerbations and progression to severe disease. The role of severe acute respiratory syndrome coronavirus (SARS-CoV-2) in exacerbations of asthma or the influence of preexisting viral or allergic airway inflammation on the development of coronavirus disease 2019 (COVID-19) is largely unknown. To address this, we compared molecular mechanisms of HDM, RV a...
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Last. Anna Puigdellívol-Sánchez (UB: University of Barcelona)H-Index: 12
view all 11 authors...
BACKGROUND: Some authors have reported that angiotensin converter enzyme inhibitors (ACEI) and angiotensin receptor blockers (ARB) improve clinical outcomes in hypertensive COVID-19 patients, and others have proposed cross-protection for influenza vaccination. This study explores the impact of these variables on the evolution of hospitalized patients, focusing in the first wave and the Delta wave. METHODS: Hospitalizations (n=1888) from March 1, 2020, to July 31, 2021, in the Hospital of Terrass...
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