Papers 292
1 page of 30 pages (292 results)
#1Lei Kang (HKUST: Hong Kong University of Science and Technology)H-Index: 1
#2Xiufeng Li (HKUST: Hong Kong University of Science and Technology)H-Index: 2
Last. Terence T. W. Wong (HKUST: Hong Kong University of Science and Technology)H-Index: 14
view all 4 authors...
Abstract null null Histological images can reveal rich cellular information of tissue sections, which are widely used by pathologists in disease diagnosis. However, the gold standard for histopathological examination is based on thin sections on slides, which involves inevitable time-consuming and labor-intensive tissue processing steps, hindering the possibility of intraoperative pathological assessment of the precious patient specimens. Here, by incorporating ultraviolet photoacoustic microsco...
#1Shengfu Cheng (PolyU: Hong Kong Polytechnic University)H-Index: 1
#2Yingying Zhou (PolyU: Hong Kong Polytechnic University)H-Index: 7
Last. Puxiang Lai (PolyU: Hong Kong Polytechnic University)H-Index: 18
view all 6 authors...
Abstract null null Optical-resolution photoacoustic microscopy (OR-PAM) enjoys superior spatial resolution and has received intense attention in recent years. The application, however, has been limited to shallow depths because of strong scattering of light in biological tissues. In this work, we propose to achieve deep-penetrating OR-PAM performance by using deep learning enabled image transformation on blurry living mouse vascular images that were acquired with an acoustic-resolution photoacou...
#1Cao Duong Ly (Pukyong National University)H-Index: 2
#2Van Tu Nguyen (Pukyong National University)H-Index: 8
Last. Junghwan OhH-Index: 34
view all 9 authors...
Abstract null null Photoacoustic (PA) microscopy allows imaging of the soft biological tissue based on optical absorption contrast and spatial ultrasound resolution. One of the major applications of PA imaging is its characterization of microvasculature. However, the strong PA signal from skin layer overshadowed the subcutaneous blood vessels leading to indirectly reconstruct the PA images in human study. Addressing the present situation, we examined a deep learning (DL) automatic algorithm to a...
#7Ivy H. M. Wong (HKUST: Hong Kong University of Science and Technology)H-Index: 1
#1Jinhwan Kim (Georgia Institute of Technology)H-Index: 19
#2Anthony Yu (Georgia Institute of Technology)H-Index: 1
Last. Stanislav Emelianov (Georgia Institute of Technology)H-Index: 75
view all 4 authors...
Abstract null null Matrix metalloproteinase-9 (MMP-9) plays major roles in extracellular matrix (ECM) remodeling and membrane protein cleavage, suggesting a high correlation with cancer cell invasion and tumor metastasis. Here, we present a contrast agent based on a DNA aptamer that can selectively target human MMP-9 in the tumor microenvironment (TME) with high affinity and sensitivity. Surface modification of plasmonic gold nanospheres with the MMP-9 aptamer and its complementary sequences all...
#1Yang Liu (HIT: Harbin Institute of Technology)
#2Tommaso Seresini (Katholieke Universiteit Leuven)
Last. Christ Glorieux (Katholieke Universiteit Leuven)H-Index: 33
view all 7 authors...
Abstract null null Light absorption induced thermoelastic and photoacoustic excitation, combined with laser Doppler vibrometry, was utilized to analyze the dynamic mechanical behavior of a microcantilever. The measured frequency response, modal shapes, and acoustic coupling effects were interpreted in the framework of a simple Bernouilli-Euler model and quantitative 3D finite element method (FEM) analysis. Three opto-mechanical generation mechanisms, each initiated by modulated optical absorptio...
#1Cheng Chen (Peking Union Medical College Hospital)H-Index: 2
#2S Z Liu (Peking Union Medical College Hospital)H-Index: 5
view all 13 authors...
Multiple objective assessments have been used to assess the activity of keloids to compare different therapeutic regimens and facilitate the best individual treatment choice for patients, but none of them are standardized. A multimodal photoacoustic/ultrasonic (PA/US) imaging system, including photoacoustic imaging, elastography, ultra-micro-angiography, and conventional US technologies (gray scale US, color Doppler US, and power Doppler US), was applied to evaluate keloids by a radiologist. Gro...
#1David Thompson (UT: University of Twente)H-Index: 2
#2J. R. Nagel (UT: University of Twente)H-Index: 1
Last. Srirang Manohar (UT: University of Twente)H-Index: 32
view all 4 authors...
Abstract null null We present a protocol for the design, fabrication and characterisation of laser-induced ultrasound transmitters with a specific, user-defined frequency response for the purpose of ultrasound tomography of large-volume biomedical samples. Using an analytic solution to the photoacoustic equation and measurements of the optical and acoustic properties of the materials used in the transmitters, we arrive at a required mixture of carbon black and polydimethylsiloxane to achieve the...
#1Adrian P. Regensburger (FAU: University of Erlangen-Nuremberg)H-Index: 4
#2Alexandra L. Wagner (FAU: University of Erlangen-Nuremberg)H-Index: 3
Last. Ferdinand Knieling (FAU: University of Erlangen-Nuremberg)H-Index: 10
view all 15 authors...
Abstract null null Proximal spinal muscular atrophy (SMA) is a rare progressive, life limiting genetic motor neuron disease. While promising causal therapies are available, meaningful prognostic biomarkers for therapeutic monitoring are missing. We demonstrate handheld Multispectral Optoacoustic Tomography (MSOT) as a novel non-invasive imaging approach to visualize and quantify muscle wasting in pediatric SMA. While MSOT signals were distributed homogeneously in muscles of healthy volunteers (H...
#1Eric SeifertH-Index: 5
#2Jan Tode (Hochschule Hannover)
Last. Ralf Brinkmann (University of Lübeck)H-Index: 32
view all 9 authors...
Abstract null null Objectives null Selective Retina Therapy (SRT) uses microbubble formation (MBF) to target retinal pigment epithelium (RPE) cells selectively while sparing the neural retina and the choroid. Intra- and inter-individual variations of RPE pigmentation makes frequent radiant exposure adaption necessary. Since selective RPE cell disintegration is ophthalmoscopically non-visible, MBF detection techniques are useful to control adequate radiant exposures. It was the purpose of this st...
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