In this study we used spectrophotometrical techniques to estimate antioxidant efficacy by using 2,2-diphenyl-1-picrylhydrazyl free radical scavenging capacity and reducing power capacity. We have used also electrochemical techniques performed by cyclic voltammetry. The present study examined the antioxidant activities of the methanolic extract (ME) of date palm (Phoenix dactylifera. L) fruits (DPF) of four native cultivars from Algeria, namely, Ghars (Gh), Chtaya (Cht), Degla Beïda (DB) and Tini...
Novel coordination complexes of Co, Mn and Fe with Azomethine (E)-2-(decan-2-ylidene) hydrazine-1-carboxamide have been synthesized and studied using elemental analysis (C, H, N), FT-IR, 1HNMR, 13 CNMR, XRD and Mass spectroscopy as well as thermal studies. The Schiff base has octahedral geometry and functions as a tridentate ONS donor ligand. The antimicrobial action of the Azomethine ligand and complexes was investigated towards Staphylococcus aureus, Escherichia coli and fungi C. albicans and ...
In this study, a novel series of heterocyclic compounds containing pyrazoline nucleus has been synthesized. The compounds were synthesized in two steps. Chalcone was synthesized in the first step by Claisen-Schmidt reaction, using 1-acetylnaphthalene and p-nitrobenzaldehyde as reactants. In the second step, the chalcone was cyclized in an acidic medium with some hydrazine derivatives to form pyrazolines. All the compounds were characterized by physical, chromatographic, spectroscopic, and elemen...
A novel series of novel 5-[(9H-carbazol-9-yl)methyl]-N-[(substituted phenyl)(piperazin-1-yl)methyl]-1,3,4-oxadiazol-2-amines (4a–o) products were synthesized from starting material of carbazole, which were on reacted with ethyl chloro-acetate yielded to form ethyl 2-(9H-carbazole-9-yl)acetate (1). Compound 1 on reacted with semicarbazide followed by cyclisation by sulphuric acid to give 5-((9H-carbazole-9-yl)-1,3,4-oxadiazol-2-amine (3), which through Mannich condensation with piperazine and a v...
The main objective of the present study is to give a general view of gas-generating floating tablets and past work done on them. The authors gave an overview of gas-generating floating tablets by referring to peer-reviewed journals, magazines, and books. The data so obtained was encrypted and compiled. The outcome of this data is the generation of a literature that helps the researchers quickly refer to the pasty work done on the gastro-retentive floating tablets. The study concludes that the ga...
The structural confirmation of the (E)-1-(4-Chlorophenyl)-3-(4-methylphenyl)prop-2-en-1-one compound is done by experimental techniques. Experimental techniques FTIR, proton NMR, UV-Visible, performed for the compound. The experimentally obtained results are compared with theoretically (density functional theory) obtained results. The decomposition and melting point of the compound is obtained by TGA and DTA. Density functional theory is performed for the (E)-1-(4-Chlorophenyl)-3-(4-methylphenyl...
In this review we explain all the detailed information about Microwave assisted synthesis. Now a days the Microwave very much beneficial in to Microwave assisted synthesis reaction for green chemistry work by the various reactions. this is initially used by the save energy and rate of reaction is fast. Microwave synthesis capable of predicting many properties and rate of synthesis reaction is fast in small period of time to get from product. all type chemical reaction synthesis is also done by t...
#1K.P. Beena(Sri Ramakrishna Institute of Paramedical Sciences)
#2G. Sathya Pooja(Sri Ramakrishna Institute of Paramedical Sciences)
Heterocycles occupy a salient place in chemistry due to their wide range of activity in the fields of drug design, photochemistry, agrochemicals, dyes, and so on. Amongst all, Pyranocoumarin scaffold is considered as one of the most promising heterocycles found in natural and synthetic sources and has been shown to possess various biological activities including anti-inflammatory, anti-HIV, antitubercular, anti HBV, anti-dyslipidemic, antiplatelet, anti-inflammatory, antioxidant and antibacteria...
A novel reverse phase liquid chromatographic method was developed and validated for estimation of Albuterol sulphate in its dosage form i.e. tablets. The reverse phase HPLC analysis was carried out on isocratic system. The column was Hypersil BDS C18 (150mm x 4.6mm, 5µm) with ambient temperature. The mobile phase consisted of buffer: methanol in proportion 75:25 % (v/v). The flow rate was maintained at 1.0ml/min. The detection was carried out at wavelength 225nm. The method was validated as per ...
A simple, sensitive, accurate, rapid and economical Spectrophotometric method was developed for estimation and validation of Remogliflozin Etabonate in pure drug and tablet dosage form. The absorbance was measured at 239.8nm using Ethanol as solvent system. It obeyed Beer’s law at the concentration range of 2-14µg/ml with coefficient of correlation (r2) of 0.997. Limit of detection (LOD) was found to be 1.220µg/ml and Limit of quantitation (LOQ) was found to be 5.220µg/ml. The proposed analytica...
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