European urology focus
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Papers 1124
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#1Charlotte T.J. Michels (Radboud University Nijmegen)H-Index: 4
#2Carl J. WijburgH-Index: 2
Last. Ilze E.W. van OnnaH-Index: 2
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Abstract null null Background null Open radical cystectomy (ORC) is regarded as the standard treatment for muscle-invasive bladder cancer, but robot-assisted radical cystectomy (RARC) is increasingly used in practice. A recent study showed that RARC resulted in slightly fewer minor but slightly more major complications, although the difference was not statistically significant. Some differences were found in secondary outcomes favouring either RARC or ORC. RARC use is expected to increase in com...
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#1Said Ourfali (UCBL: Claude Bernard University Lyon 1)
#2Xavier Matillon (UCBL: Claude Bernard University Lyon 1)H-Index: 5
Last. Marc Colombel (UCBL: Claude Bernard University Lyon 1)H-Index: 16
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Abstract null null Background null Delay in treatment is a prognostic factor in muscle-invasive bladder cancer. null null null Objective null To evaluate clinical outcomes associated with delays in diagnosis and treatment for patients with non–muscle invasive bladder cancer (NMIBC). null null null Design, setting, and participants null In this retrospective study we analyzed data for patients treated at our center between November 2008 and December 2016 for intermediate risk (IR) or high risk (H...
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#1Beshara Sheehan (ICR: Institute of Cancer Research)H-Index: 1
#2Christina Guo (The Royal Marsden NHS Foundation Trust)H-Index: 4
Last. Johann S. de Bono (The Royal Marsden NHS Foundation Trust)H-Index: 124
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Abstract null null Context null Prostate-specific membrane antigen (PSMA) is a promising, novel theranostic target in advanced prostate cancer (PCa). Multiple PSMA-targeted therapies are currently in clinical development, with some agents showing impressive antitumour activity, although optimal patient selection and therapeutic resistance remain ongoing challenges. null null null Objective null To review the biology of PSMA and recent advances in PSMA-targeted therapies in PCa, and to discuss po...
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#1Heidi Wagner (Princess Margaret Cancer Centre)
#2Miran Kenk (Princess Margaret Cancer Centre)H-Index: 14
Last. Neil Fleshner (Princess Margaret Cancer Centre)H-Index: 73
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Abstract null null Context null Translational research in uro-oncology depends on the availability of high-quality biospecimens and associated data to advance precision medicine and improve clinical outcomes. Procurement, storage, and annotation of these specimens represent critical steps towards this end. null null null Objective null To review best-practice experiences gained via the McCain GU BioBank, a repository of more than 750 000 biospecimens obtained from more than 16 000 patients atten...
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#1Umberto CarbonaraH-Index: 3
#2Fabio Crocerossa (Magna Græcia University)H-Index: 4
Last. Jihad H. KaoukH-Index: 98
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Abstract null null Context null Live surgical broadcast (LSB), also known as live surgery, has become a popular format for many types of surgical education meetings. However, concerns have been raised in relation to patient safety, ethical issues, and the actual educational value of LSB. null null null Objective null To summarize current evidence on LSB with a focus on the risks of complications and the educational impact. null null null Evidence acquisition null We performed a systematic review...
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#1Sulayman Benmerzoug (CHUV: University Hospital of Lausanne)
#2Mathieu F. Chevalier (CHUV: University Hospital of Lausanne)H-Index: 13
Last. Patrice Jichlinski (CHUV: University Hospital of Lausanne)H-Index: 32
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Abstract null null Among the growing family of inhibitory receptors regulating immunity, sialic acid–binding immunoglobulin domain–containing lectins (Siglecs) have recently emerged as immunoregulatory receptors recognizing sialylated ligands on tumor cell surface. However, their role in the immunoregulation of bladder cancer (BCa) remains unknown. Here, we determined the presence of eight Siglec ligands (SLs) on bladder nontumor and tumor cell lines. S2L, S3L, and S6L were not expressed, and fe...
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BACKGROUND Hospital volume is considered to be a quality measure for outcomes after major oncological surgery. However, countrywide data are lacking for radical prostatectomy (RP). OBJECTIVE To assess the impact of hospital volume on postoperative outcomes after RP performed using an open (ORP) versus a minimally invasive surgery (MIS, including pure and robot-assisted RP) approach. DESIGN, SETTING, AND PARTICIPANTS Data for patients undergoing RP in France from 2014 to 2019 were extracted from ...
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#1Lisa Moris (Katholieke Universiteit Leuven)H-Index: 11
#2Giorgio Gandaglia (UniSR: Vita-Salute San Raffaele University)H-Index: 47
Last. Ann Henry (St James's University Hospital)H-Index: 32
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Abstract null null Context null Surgical techniques aimed at preserving the neurovascular bundles during radical prostatectomy (RP) have been proposed to improve functional outcomes. However, it remains unclear if nerve-sparing (NS) surgery adversely affects oncological metrics. null null null Objective null To explore the oncological safety of NS versus non-NS (NNS) surgery and to identify factors affecting the oncological outcomes of NS surgery. null null null Evidence acquisition null Relevan...
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#1Ekaterina Laukhtina (Medical University of Vienna)H-Index: 7
#2Pawel Rajwa (Medical University of Silesia)H-Index: 5
Last. Simone Albisinni (ULB: Université libre de Bruxelles)H-Index: 14
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Context null The question of the ability of frozen section analysis (FSA) to accurately detect malignant pathology intraoperatively has been discussed for many decades. null Objective null We aimed to conduct a systematic review and meta-analysis assessing the diagnostic estimates of FSA of the urethral and ureteral margins in patients treated with radical cystectomy (RC) for bladder cancer (BCa). null Evidence acquisition null The MEDLINE and EMBASE databases were searched in February 2021 for ...
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#1Annika Reinke (DKFZ: German Cancer Research Center)H-Index: 2
#1Annika Reinke (DKFZ: German Cancer Research Center)H-Index: 7
Last. Lena Maier-Hein (DKFZ: German Cancer Research Center)H-Index: 32
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Abstract null null With the impact of artificial intelligence (AI) algorithms on medical research on the rise, the importance of competitions for comparative validation of algorithms, so-called challenges, has been steadily increasing, to a point at which challenges can be considered major drivers of research, particularly in the biomedical image analysis domain. Given their importance, high quality, transparency, and interpretability of challenges is essential for good scientific practice and m...
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Top fields of study
Urology
Surgery
Oncology
Context (language use)
Prostate cancer
Medicine