Journal of orthopaedic translation
IF
5.19
Papers
788
Papers 767
1 page of 77 pages (767 results)
#1Sheng Chen (HUST: Huazhong University of Science and Technology)H-Index: 2
#2Mingjue Chen (SUSTech: Southern University of Science and Technology)H-Index: 1
Last. Guozhi Xiao (SUSTech: Southern University of Science and Technology)H-Index: 48
view all 8 authors...
Abstract null null Background null To comprehensively analyze the global level and trends of prevalence, incidence and years lived with disability (YLDs) for low back pain (LBP) from 1990 to 2019 by age, sex and sociodemographic index (SDI). null null null Methods null Publicly available modelled data and methods were obtained from the Global Burden of Diseases (GBD) study 2019, and used to evaluate the global burden of LBP through a systematic analysis. null null null Results null Globally, the...
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#1Chao Ye (BUCM: Beijing University of Chinese Medicine)H-Index: 2
#2Jing Chen (BUCM: Beijing University of Chinese Medicine)H-Index: 2
Last. Pengyang Li (BUCM: Beijing University of Chinese Medicine)H-Index: 2
view all 9 authors...
Abstract null null Objective null Based on the expression changes in the TGF-β/ALK5/Smad2/3 signal transduction pathway, the repair of cartilage injury in the rabbit knee joint was investigated and evaluated by oral administration of naringin in combination with acellular dermal matrix implantation. null null null Methods null First, twenty New Zealand white rabbits were randomly divided into five groups: a sham operation group (Sham group), a model group (Mod group), a naringin group (Nar group...
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#1Yiyang Ma (SJTU: Shanghai Jiao Tong University)
#2Kaiwen Zheng (SJTU: Shanghai Jiao Tong University)
Last. Dajiang Du (SJTU: Shanghai Jiao Tong University)H-Index: 1
view all 7 authors...
Abstract null null Background null Costal chondrocytes (CCs), as a promising donor cell source for cell-based therapy for cartilage repair, have strong tendency of hypertrophy and calcification, which limited CCs from further application in cartilage regenerative medicine. Synovium-derived stromal cells (SDSCs), have shown their beneficial effect for chondrocytes to maintain phenotype. This study aims to investigate whether SDSCs could help CCs to maintain chondrogenic phenotype and suppress hyp...
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#1Ke Lu (CAS: Chinese Academy of Sciences)H-Index: 3
#2Feng Ma (CAS: Chinese Academy of Sciences)
Last. Di Chen (CAS: Chinese Academy of Sciences)H-Index: 49
view all 6 authors...
Abstract null null Objective null Temporomandibular joint (TMJ) osteoarthritis (OA) is a type of TMJ disorders with clinical symptoms of pain, movement limitation, cartilage degeneration and joint dysfunction. This review article is aiming to summarize recent findings on signaling pathways involved in TMJ OA development and progression. null null null Methods null Most recent findings in TMJ OA studies have been reviewed and cited. null null null Results null TMJ OA is caused by inflammation, ab...
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#1Feng Zhou (SJTU: Shanghai Jiao Tong University)H-Index: 8
#2Xuequan Han (SJTU: Shanghai Jiao Tong University)H-Index: 7
Last. Mengning Yan (SJTU: Shanghai Jiao Tong University)H-Index: 10
view all 14 authors...
Abstract null null Background/objective null Subchondral bone marrow lesions (BMLs) are common magnetic resonance imaging (MRI) features in joints affected by osteoarthritis (OA), however, their clinical impacts and mechanisms remain controversial. Thus, we aimed to investigate subchondral BMLs in knee OA patients who underwent total knee arthroplasty (TKA), then evaluate the associations of osteoclastogenesis and nerve growth in subchondral BMLs with clinical symptoms. null null null Methods nu...
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#1Xiaohao Wu (SUSTech: Southern University of Science and Technology)H-Index: 2
#2Minghao Qu (SUSTech: Southern University of Science and Technology)
Last. Guozhi Xiao (SUSTech: Southern University of Science and Technology)H-Index: 48
view all 6 authors...
Abstract null null Background null Our recent studies demonstrate that the focal adhesion protein Kindlin-2 exerts crucial functions in the mesenchymal stem cells, mature osteoblasts and osteocytes in control of early skeletal development and bone homeostasis in mice. However, whether Kindlin-2 plays a role in osteoprogenitors remains unclear. null null null Materials and methods null Mice lacking Kindlin-2 expression in osterix (Osx)-expressing cells (i.e., osteoprogenitors) were generated. Mic...
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#1Yiwei Chen (SJTU: Shanghai Jiao Tong University)
#2Yu Miao (SJTU: Shanghai Jiao Tong University)
Last. Guangyi Li (SJTU: Shanghai Jiao Tong University)H-Index: 6
view all 7 authors...
Abstract null null Osteonecrosis of the femoral head (ONFH) is a recalcitrant ischemic disorder, which could be classified into two major categories: traumatic and nontraumatic. Regardless of different risk factors, it has been testified that ONFH results from primitive vascular problems, leading to temporary or permanent loss of blood supply to bone tissue. Histopathological and microarchitectural alterations ensues, which is a gradual evolutionary process involving bone marrow and osteocyte ne...
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#1Kenneth Lo (HKPU: Hong Kong Polytechnic University)H-Index: 11
#2Manting Au (HKPU: Hong Kong Polytechnic University)H-Index: 1
Last. Chunyi Wen (HKPU: Hong Kong Polytechnic University)H-Index: 22
view all 4 authors...
Abstract null null Objective null Literature examining the relationship between elevated blood pressure and osteoarthritis (OA) has yielded conflicting results. This study aimed to systematically review the relationship between hypertension and OA in both load-bearing and non-load-bearing joints. null null null Methods null A systematic literature search was performed on Embase, Emcare, MEDLINE and Ovid Nursing Database. The associations between hypertension and OA development in knees, hips and...
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#1Wenxiang ChengH-Index: 11
#2Yan-Zhi LiuH-Index: 1
Last. Hu-Dan PanH-Index: 1
view all 13 authors...
Objectives null Vascularization is an essential step in successful bone tissue engineering. The induction of angiogenesis in bone tissue engineering can be enhanced through the delivery of therapeutic agents that stimulate vessel and bone formation. In this study, we show that cucurbitacin B (CuB), a tetracyclic terpene derived from Cucurbitaceae family plants, facilitates the induction of angiogenesis in vitro. null Methods null We incorporated CuB into a biodegradable poly (lactide-co-glycolid...
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#1Bo Li (Beijing Jishuitan Hospital)
#2Lingjia Yu (CUMS: Capital Medical University)
Last. Yu Zhao (PUMCH: Peking Union Medical College Hospital)H-Index: 13
view all 6 authors...
Abstract null null Background null Interruption of blood supply will lead to necrosis of body tissues, such as osteonecrosis of femoral head (ONFH). Vascularization has always been regarded as one of the biggest challenges in tissue engineering. In the current study, a novel device was proposed to reconstruct blood supply of necrotic femoral head. null null null Methods null Cryo-insult with liquid nitrogen method was adopted to establish the ONFH model. In experimental group, a novel scaffold c...
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