International journal of breast cancer
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241
Papers 247
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#1Tamera J. Lillemoe (Allina Health)H-Index: 3
#2Mara Hester Rendi (Allina Health)
Last. Karen K. Swenson (Allina Health)H-Index: 19
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#1Nirmala Ghimirey (KSU: Kent State University)H-Index: 1
#2Chase Steele (KSU: Kent State University)H-Index: 1
Last. Loral E. Showalter (KSU: Kent State University)H-Index: 4
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Although immune-based therapies have made remarkable inroads in cancer treatment, they usually must be combined with standard treatment modalities, including cytotoxic drugs, to achieve maximal clinical benefits. As immunotherapies are further advanced and refined, considerable efforts will be required to identify combination therapies that will maximize clinical responses while simultaneously decreasing the unpleasant and sometimes life-threatening side effects of standard therapy. Over the las...
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#1Roya Dolatkhah (Tabriz University of Medical Sciences)H-Index: 13
#2Mohammad Hossein Somi (Tabriz University of Medical Sciences)H-Index: 27
Last. Saeed Dastgiri (Tabriz University of Medical Sciences)H-Index: 21
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#1Jennifer Segar (UA: University of Arizona)H-Index: 2
#2Ritu Pandey (UA: University of Arizona)H-Index: 12
Last. Pavani Chalasani (UA: University of Arizona)H-Index: 13
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Pleomorphic invasive lobular carcinoma (PILC) is a distinct morphological and biologically aggressive variant of invasive lobular carcinoma (ILC). We hypothesized that was due to de novo activation of PI3K/Akt/mTOR pathway in PILC resulting in higher proliferation rate and markers of cell cycle activation. We identified PILC and ILC tumors and tested for PI3K/Akt/mTOR pathway activation by immunohistochemistry (PTEN and pS6K1) and gene expression analysis (by Nanostring nCounter system). Prolife...
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#1Karima Oualla (Sidi Mohamed Ben Abdellah University)H-Index: 5
#2Loay Kassem (Cairo University)H-Index: 10
Last. Nawfel Mellas (Sidi Mohamed Ben Abdellah University)H-Index: 9
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Triple-negative breast cancer (TNBC) is characterized by the absence of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2). It accounts for 15%-20% of all breast cancers and is associated with an aggressive evolution and poor outcomes with the majority of recurrences and deaths occurring in the first 5 years. Chemotherapy remains the mainstay of treatment in the absence of effective targets, but the good understanding of immune tumor microenvi...
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Background. Breast cancer in men is a rare condition, often diagnosed late. The purpose of this study was to describe its epidemiological, histopathological, and radiographic aspects in Togo. Materials and Methods. This was a descriptive retrospective study on cases of breast cancer in humans diagnosed histologically at the Laboratory of Anatomy Pathological and Imagery of the University Hospital in Lome, over a period of 25 years (1995 to 2019). The parameters studied were epidemiological, anat...
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#1Elizabeth Anderson (UA: University of Arizona)H-Index: 24
#1Elizabeth J. Anderson (UA: University of Arizona)H-Index: 4
Last. Lisa E. Davis (UA: University of Arizona)H-Index: 14
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PIK3CA mutation frequency varies among breast cancer (BC) subtypes. Recent evidence suggests combination therapy with the PI3K inhibitor (PI3Ki) alpelisib and endocrine therapy (ET) improves response rates and progression-free survival (PFS) in PIK3CA-mutant, hormone receptor positive (HR+) BC versus ET alone; thus, better understanding the clinical and epidemiologic elements of these mutations is warranted. This systematic review characterizes the PIK3CA mutation epidemiology, type of testing a...
2 CitationsSource
#1Roya Dolatkhah (Tabriz University of Medical Sciences)H-Index: 13
#1Roya Dolatkhah (Tabriz University of Medical Sciences)H-Index: 1
Last. Saeed Dastgiri (Tabriz University of Medical Sciences)H-Index: 21
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Background and Aim. Breast cancer is the most frequent cancer in women and the second most common cancer across the globe. The aim of this study was to report the survival data and trend analysis of breast cancer between 2007 and 2016 in a northwest region in Iran. Methods. Data were obtained from East Azerbaijan cancer registry database for the 10-year period between 2007 and 2016. Survival analysis was performed to calculate the breast cancer-specific survival proportions and mortality rates. ...
2 CitationsSource
#1Tatiana KalininaH-Index: 3
Last. L. F. Gulyaeva (NSU: Novosibirsk State University)H-Index: 10
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Breast cancer is the most commonly diagnosed cancer among women. Difficulties in treating breast cancer are associated with the occurrence of metastases at early stages of disease, leading to its further progression. Recent studies have shown that changes in androgen receptor (AR) and microRNAs’ expressions are associated with mammary gland carcinogenesis, in particular, with the formation of metastases. Thus, to identify novel metastatic markers, we evaluated the expression levels of AR; miR-18...
5 CitationsSource
#1Engida AbebeH-Index: 4
#2Kassaw DemilieH-Index: 1
Last. Kirubel AbebeH-Index: 3
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Background. Mastectomy is the most common form of treatment for a developing-nation woman diagnosed with breast cancer. This can have huge effect on a women’s quality of life. Objective. To assess mastectomy-related quality of life in female breast cancer patients. Materials and Methods. A facility-based cross-sectional descriptive study was conducted from February 1st to July 30th, 2018. A pretested structured data collection format was used to interview patients. The European Organization for ...
1 CitationsSource
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