Antimicrobial Resistance and Infection Control
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#1Qingwen Deng (Fujian Medical University)
#2Zhichao Zeng (Fujian Medical University)
Last. Wenbin Liu (Fujian Medical University)
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BACKGROUND With inappropriate use of antimicrobials becoming a great public health concern globally, the issue of applying clinical practice guidelines (CPGs) to regulate the rational use of antimicrobials has attracted increasing attention. Taking tertiary general hospitals in China for example, this study aimed to identify factors to investigate the comprehensive influencing mechanism for physicians' intention to use CPGs on antimicrobials. METHODS Based on the integration of Theory of Planned...
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#1Cihan Papan (Saarland University)H-Index: 5
#2Matthias Schröder (Saarland University)
Last. Alexander MellmannH-Index: 61
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BACKGROUND The unrestricted use of linezolid has been linked to the emergence of linezolid-resistant Staphylococcus epidermidis (LRSE). We report the effects of combined antibiotic stewardship and infection control measures on the spread of LRSE in an intensive care unit (ICU). METHODS Microbiological data were reviewed to identify all LRSE detected in clinical samples at an ICU in southwest Germany. Quantitative data on the use of antibiotics with Gram-positive coverage were obtained in defined...
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#2Niloofar Sabokroo (Shahid Sadoughi University of Medical Sciences and Health Services)H-Index: 1
Last. Ebrahim Kouhsari (Golestan University)H-Index: 6
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BACKGROUND Vancomycin‑resistant Staphylococcus aureus (VRSA) is a serious public health challenging concern worldwide. OBJECTIVES Therefore, the objective of present study of 62 published studies was to evaluate the prevalence of VRSA based on different years, areas, isolate source, antimicrobial susceptibility testing, and the genetic determinants. METHODS We searched the relevant articles that focused on the prevalence rates of VRSA in PubMed, Scopus, Embase, and Web of Science from 2000 to 20...
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#1Yangmin Hu (ZJU: Zhejiang University)
#2Danyang Li (ZJU: Zhejiang University)
Last. Haibin Dai (ZJU: Zhejiang University)H-Index: 19
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BACKGROUND Infection is the leading cause of morbidity and mortality among burn patients, and bloodstream infection (BSI) is the most serious. This study aimed to evaluate the epidemiology and clinical outcomes of BSI in severe burn patients. METHODS Clinical variables of all patients admitted with severe burns (≥ 20% total body surface area, %TBSA) were analyzed retrospectively from January 2013 to December 2018 at a teaching hospital. The Kaplan-Meier method was utilized for plotting survival ...
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#1Pandolfo Am (British Medical Association)
#2Horne R (British Medical Association)
Last. Stephen J. Brett (Imperial College London)H-Index: 41
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BACKGROUND Rapid molecular diagnostic tests to investigate the microbial aetiology of pneumonias may improve treatment and antimicrobial stewardship in intensive care units (ICUs). Clinicians' endorsement and uptake of these tests is crucial to maximise engagement; however, adoption may be impeded if users harbour unaddressed concerns or if device usage is incompatible with local practice. Accordingly, we strove to identify ICU clinicians' beliefs about molecular diagnostic tests for pneumonias ...
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#1Yolandi Snyman (UCT: University of Cape Town)H-Index: 2
#2Andrew Whitelaw (National Health Laboratory Service)H-Index: 35
Last. Mae Newton-Foot (National Health Laboratory Service)H-Index: 7
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BACKGROUND Colistin is regarded as a last-resort antimicrobial against multi-drug resistant Gram-negative bacteria (GNB), therefore the dissemination of colistin resistance in the environment is of great concern. Horizontal transfer of mobile colistin resistance (mcr) genes to potential pathogens poses a serious problem. This study aimed to describe the presence of colistin resistant GNB and mcr genes in river and storm water in regions of the Western Cape. METHODS Water samples were collected f...
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BACKGROUND The emergence and spread of antimicrobial resistance and infectious agents have challenged hospitals in recent decades. Our aim was to investigate the circulation of target infectious agents using Geographic Information System (GIS) and spatial-temporal statistics to improve surveillance and control of healthcare-associated infection and of antimicrobial resistance (AMR), using Klebsiella pneumoniae complex as a model. METHODS A retrospective study carried out in a 450-bed federal, te...
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BACKGROUND Accessibility to alcohol-based handrub (ABHR) dispenser is crucial to improve compliance to hand hygiene (HH), being offered as wall-mounted dispensers (ABHR-Ds), and/or pocket bottles. Nevertheless, information on the distribution and density of ABHR-Ds and their impact on HH have hardly been studied. Institutions such as the World Health Organisation or the Centers for Disease Control and Prevention do not provide guidance. The Robert-Koch-Institute (RKI) from Germany recommends an ...
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BACKGROUND Antimicrobial resistance (AMR) is one of the greatest global health challenges today, but burden assessment is hindered by uncertainty of AMR prevalence estimates. Geographical representation of AMR estimates typically pools data collected from several laboratories; however, these aggregations may introduce bias by not accounting for the heterogeneity of the population that each laboratory represents. METHODS We used AMR data from up to 381 laboratories in the United States from The S...
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Background null Understaffing has been previously reported as a risk factor for central line-associated bloodstream infections (CLABSI). No previous study addressed the question whether fluctuations in staffing have an impact on CLABSI incidence. We analyzed prospectively collected CLABSI surveillance data and data on employee turnover of health care workers (HCW) to address this research question. null Methods null In January 2016, a semiautomatic surveillance system for CLABSI was implemented ...
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Top fields of study
Drug resistance
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Infection control
Intensive care medicine
Medical microbiology
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Antibiotic resistance