Analytical Chemistry
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#1Xiaodi Rong (University of Jinan)H-Index: 1
#2Caiyun Liu (University of Jinan)H-Index: 21
Last. Baocun Zhu (University of Jinan)H-Index: 33
view all 12 authors...
Cancer is a serious threat to human health, and there is an urgent need to develop new treatment methods to overcome it. Organelle targeting therapy, as a highly effective and less toxic side effect treatment strategy, has great research significance and development prospects. Being an essential organelle, the Golgi apparatus plays a particularly major role in the growth of cancer cells. Acting as an indispensable and highly expressed antioxidant in cancer cells, glutathione (GSH) also contribut...
#1Haonan Li (CQU: Chongqing University)H-Index: 1
#2Long Jiao (CQU: Chongqing University)H-Index: 8
Last. Qiang Liao (CQU: Chongqing University)H-Index: 44
view all 9 authors...
The light-enabled droplet levitation shows promising potential in applications in biotechnology, clinical medicine, and nanomaterials. In particular, light-levitated droplets have good followability with a moving laser beam, resulting in flexibility in manipulating their motion. However, it is still unclear whether there exists an upper limit to the light-levitated droplet motion with a moving laser beam. Therefore, the motion of light-levitated droplets above the free interface is studied to de...
#1Mengxi Chen (CUG: China University of Geosciences)H-Index: 1
#2Ruilin Duan (CUG: China University of Geosciences)H-Index: 4
Last. Fujian Huang (CUG: China University of Geosciences)H-Index: 17
view all 7 authors...
Specific and sensitive detection and imaging of cancer-related miRNA in living cells are desirable for cancer diagnosis and treatment. Because of the spatiotemporal variability of miRNA expression level during different cell cycles, signal amplification strategies that can be activated by external stimuli are required to image miRNAs on demand at desired times and selected locations. Herein, we develop a signal amplification strategy termed as the photoactivated DNA walker based on DNA nanoflare...
#1Nannan Wu (CCNU: Central China Normal University)H-Index: 3
#2Lei Jiao (CCNU: Central China Normal University)H-Index: 23
Last. Chengzhou Zhu (CCNU: Central China Normal University)H-Index: 72
view all 10 authors...
Rational design and construction of advanced sensing platforms for sensitive detection of H2O2 released from living cells is one of the challenges in the field of physiology and pathology. Noble metal clusters are a kind of nanomaterials with well-defined chemical composition and special atomic structures, which have been widely explored in catalysis, biosensing, and therapy. Compared with noble metal nanoparticles, noble metal clusters exhibit great potential in electrochemical biosensing due t...
#1Raveendra Wickramasinghe (UIC: University of Illinois at Chicago)H-Index: 2
#2Michael J Pasterski (UIC: University of Illinois at Chicago)
Last. Luke Hanley (UIC: University of Illinois at Chicago)H-Index: 42
view all 7 authors...
The study of lipid molecular fossils by traditional biomarker analysis requires bulk sample crushing, followed by solvent extraction, and then the analysis of the extract by gas chromatography-mass spectrometry (GC-MS). This traditional analysis mixes all organic compounds in the sample regardless of their origins, with a loss of information on the spatial distribution of organic molecules within the sample. These shortcomings can be overcome using the chemical mapping of intact samples. Spectro...
#1Amit Kumar Singh (IIT KGP: Indian Institute of Technology Kharagpur)H-Index: 6
#2Asha V. Nair (IIT KGP: Indian Institute of Technology Kharagpur)H-Index: 5
Last. N. D. Pradeep Singh (IIT KGP: Indian Institute of Technology Kharagpur)H-Index: 25
view all 3 authors...
#1Brady G. Anderson (UM: University of Michigan–Ann Arbor)H-Index: 2
#2Alexander Raskind (UM: University of Michigan–Ann Arbor)H-Index: 6
Last. Charles R. Evans (UM: University of Michigan–Ann Arbor)H-Index: 18
view all 5 authors...
Untargeted metabolomics is an essential component of systems biology research, but it is plagued by a high proportion of detectable features not identified with a chemical structure. Liquid chromatography-tandem mass spectrometry (LC-MS/MS) experiments produce spectra that can be searched against databases to help identify or classify these unknowns, but many features do not generate spectra of sufficient quality to enable successful annotation. Here, we explore alterations to gradient length, m...
#1Vivian DelcourtH-Index: 9
#2Patrice GarciaH-Index: 15
view all 13 authors...
Synthetic androgenic anabolic steroids (AAS) are banned compounds and considered as major threats by both racing and sports international authorities. Hence, doping control laboratories are continually looking into analytical improvements to increase their detection capabilities, notably by means of emerging technologies. To enhance analytical performances for the detection of synthetic AAS such as stanozolol, specific chromatographic procedures have been developed using recent quaternary liquid...
#1Wei-Rong Cui (NCU: Nanchang University)H-Index: 12
#2Ya-Jie Li (NCU: Nanchang University)H-Index: 3
Last. Jian-Ding Qiu (NCU: Nanchang University)H-Index: 65
view all 8 authors...
Electrochemiluminescence (ECL), as an advanced sensing process, can selectively control the generation of excited states by changing the potential. However, most of the existing ECL systems rely on poisonous coreactants to provide radicals for luminescence; although the ECL efficiency was improved, the athematic coreactants will cause unpredictable interference to the accurate analysis of trace targets. Herein, we realized the ECL of nonemitting molecules by performing intramolecular electron tr...
#1Marc B. Taraban (UMAB: University of Maryland, Baltimore)H-Index: 9
#2Michael T. Jones (Pfizer)H-Index: 6
Last. Yihua Bruce Yu (UMAB: University of Maryland, Baltimore)H-Index: 5
view all 3 authors...
The present work reports an enabling novel technology for quantifying the gene content in adeno-associated viral capsids. The method is based on the water proton nuclear magnetic resonance (wNMR) technique. Instead of analyzing the capsid directly, it utilizes water molecules to distinguish empty and full capsids, as water interacts with them differently. The transverse relaxation rate of water protons, R2(1H2O), readily distinguishes empty and full capsids and is capable of quantifying the frac...
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