Critical Care
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#1Raffaele MarfellaH-Index: 58
#1Raffaele MarfellaH-Index: 10
Last. G. PaolissoH-Index: 1
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#2Alexis Werion (UCL: Université catholique de Louvain)H-Index: 5
#5Marie Perrot (UCL: Université catholique de Louvain)
BACKGROUND: The severity of coronavirus disease 2019 (COVID-19) is highly variable between individuals, ranging from asymptomatic infection to critical disease with acute respiratory distress syndrome requiring mechanical ventilation null Such variability stresses the need for novel biomarkers associated with disease outcome null As SARS-CoV-2 infection causes a kidney proximal tubule dysfunction with urinary loss of uric acid, we hypothesized that low serum levels of uric acid (hypouricemia) ma...
#1Gerald S. Supinski (UK: University of Kentucky)H-Index: 17
#2Paul F Netzel (UK: University of Kentucky)H-Index: 1
Last. Leigh Ann Callahan (UK: University of Kentucky)H-Index: 19
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BACKGROUND Intensive care unit acquired weakness is a serious problem, contributing to respiratory failure and reductions in ambulation. Currently, there is no pharmacological therapy for this condition. Studies indicate, however, that both beta-hydroxy-beta-methylbutyrate (HMB) and eicosapentaenoic acid (EPA) increase muscle function in patients with cancer and in older adults. The purpose of this study was to determine whether HMB and/or EPA administration would increase diaphragm and quadrice...
#1Michael S. Niederman (Cornell University)H-Index: 83
#2Rebecca M. Baron (Brigham and Women's Hospital)H-Index: 32
Last. Girish B. Nair (Oakland University)H-Index: 7
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Sepsis is a common consequence of infection, associated with a mortality rate > 25%. Although community-acquired sepsis is more common, hospital-acquired infection is more lethal. The most common site of infection is the lung, followed by abdominal infection, catheter-associated blood steam infection and urinary tract infection. Gram-negative sepsis is more common than gram-positive infection, but sepsis can also be due to fungal and viral pathogens. To reduce mortality, it is necessary to give ...
#1Jessica Gambardella (Albert Einstein College of Medicine)H-Index: 13
#2Antonietta CoppolaH-Index: 2
Last. Gaetano Santulli (Albert Einstein College of Medicine)H-Index: 52
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1 CitationsSource
#1Gianmaria Cammarota (University of Perugia)H-Index: 18
#2Elisa Rossi (University of Perugia)H-Index: 2
Last. Simonetta Tesoro (University of Perugia)H-Index: 4
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Awake prone position is an emerging rescue therapy applied in patients undergoing noninvasive ventilation (NIV) for acute hypoxemic respiratory failure (ARF) related to novel coronavirus disease (COVID-19). Although applied to stabilize respiratory status, in awake patients, the application of prone position may reduce comfort with a consequent increase in the workload imposed on respiratory muscles. Thus, we primarily ascertained the effect of awake prone position on diaphragmatic thickening fr...
#1Lucas M. Fleuren (VU: VU University Amsterdam)H-Index: 6
#2Tariq A Dam (VU: VU University Amsterdam)
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Background null The Coronavirus disease 2019 (COVID-19) pandemic has underlined the urgent need for reliable, multicenter, and full-admission intensive care data to advance our understanding of the course of the disease and investigate potential treatment strategies. In this study, we present the Dutch Data Warehouse (DDW), the first multicenter electronic health record (EHR) database with full-admission data from critically ill COVID-19 patients. null Methods null A nation-wide data sharing col...
#1Qing Pan (Zhejiang University of Technology)
#2Mengzhe Jia (Zhejiang University of Technology)
Last. Zhanqi Zhao (Furtwangen University)H-Index: 19
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#1Imane Adda (Université Paris-Saclay)H-Index: 1
#2Christopher Lai (Université Paris-Saclay)H-Index: 3
Last. Xavier Monnet (Université Paris-Saclay)H-Index: 12
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BACKGROUND Through venous contraction, norepinephrine (NE) increases stressed blood volume and mean systemic pressure (Pms) and exerts a "fluid-like" effect. When both fluid and NE are administered, Pms may not only result from the sum of the effects of both drugs. Indeed, norepinephrine may enhance the effects of volume expansion: because fluid dilutes into a more constricted, smaller, venous network, fluid may increase Pms to a larger extent at a higher than at a lower dose of NE. We tested th...
#1Sebastian J. Klein (Innsbruck Medical University)H-Index: 9
#2Timo Mayerhöfer (Innsbruck Medical University)
Last. Michael JoannidisH-Index: 40
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Top fields of study
Intensive care medicine
Emergency medicine
Intensive care unit
Intensive care