Journal of Dermatological Science
Papers 8319
1 page of 832 pages (8,319 results)
Abstract null null Background null Circular RNA (circRNA) has been confirmed to play a vital role in melanoma progression. null null null Objective null The regulatory function of circ_0062270, a novel circRNA, in melanoma progression is unclear. null null null Methods null Relative expression levels of circ_0062270 and microRNA (miR)-331-3p were determined using qRT-PCR. Cell counting kit 8 assay, EdU staining and flow cytometry were used to measure cell proliferation, cell cycle distribution a...
#1Jinwoo Hur (Konkuk University)H-Index: 5
#2Eun Sil Kang (Konkuk University)H-Index: 20
Last. Han Geuk Seo (Konkuk University)H-Index: 45
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Abstract null null Background null Previous studies suggested that the nuclear receptor peroxisome proliferator-activated receptor (PPAR)-δ plays an essential role in cellular responses against oxidative stress. null null null Objective null To investigate how PPAR-δ elicits cellular responses against oxidative stress in primary human dermal fibroblasts (HDFs) exposed to ultraviolet B (UVB). null null null Methods null The present study was undertaken in HDFs by performing real-time polymerase c...
#1Wen QinH-Index: 1
#2Huijun WangH-Index: 12
Last. Zhimiao Lin (ZJU: Zhejiang University)
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ABSTRACT null null Background null Amyloidosis cutis dyschromica (ACD) is a rare form of primary cutaneous amyloidosis featured by reticulate dotted hypo- and hyperpigmentation. Recently, loss-of-function mutations in GPNMB, encoding glycoprotein (transmembrane) nonmetastatic melanoma protein B, were found in autosomal-recessive or semi-dominant ACD. null null null Objective null This study aims to detect the genetic defect underlying ACD in nine separate cases and to investigate the functional ...
#1Rikuma Kitao (Kobe University)
#2Takeshi Fukumoto (Kobe University)H-Index: 21
Last. Chikako Nishigori (Kobe University)H-Index: 43
view all 7 authors...
#1Hideaki Uchida (Teikyo University)H-Index: 5
#2Masahiro Kamata (Teikyo University)H-Index: 18
Last. Yayoi Tada (Teikyo University)H-Index: 35
view all 9 authors...
Abstract null null Background null Apremilast, a selective inhibitor of the enzyme phosphodiesterase 4, is efficacious for psoriasis. However, detailedin vivo effects of apremilast on psoriasis remain to be elucidated. null null null Objective null To examine thein vivo effects of apremilast on psoriasis. null null null Methods null Psoriasiform dermatitis was induced by applying imiquimod (IMQ) on the murine shaved back skin for six days. Mice were treated with apremilast or vehicle intraperito...
#1Md. Al Mamun (Hamamatsu University School of Medicine)H-Index: 4
#2Ariful Islam (Hamamatsu University School of Medicine)H-Index: 4
Last. Yutaka Takahashi (Hamamatsu University School of Medicine)H-Index: 2
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Abstract null null Background null The vermilion of the human lip presents characteristic features and undergoes aging faster than the skin. Therefore, knowledge of the vermilion surface-specific functional molecules is important to understand lip aging and formulate lip care products. Previously, we analyzed the free fatty acids distributions and showed that docosahexaenoic acid highly accumulated in the vermilion's epithelium than in the skin. null null null Objective null We aimed to explore ...
#1Ziyu Wei (SJTU: Shanghai Jiao Tong University)
#2Guangjie Chen (SJTU: Shanghai Jiao Tong University)H-Index: 1
Last. Xin Li (SJTU: Shanghai Jiao Tong University)
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Abstract null null Background null Acne vulgaris is a prevalent skin disease lacking effective and well-tolerated treatment. An earlier study indicated that resveratrol (RVT) has therapeutic effects in acne patients through unknown mechanisms. null null null Objectives null To evaluate the effects of RVT on linoleic acid (LA)-induced lipogenesis and peptidoglycan (PGN)-induced inflammation in cultured SZ95 sebocytes in vitro, and to investigate the underlying mechanisms. null null null Methods n...
#1Erika Toriyama (Nagoya City University)
#2Masuda Hideyuki (Nagoya City University)H-Index: 1
Last. Akimichi Morita (Nagoya City University)H-Index: 50
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Abstract null null Background null Maximum cyclobutane pyrimidine dimer (CPD) formation in the skin induced by ultraviolet B (UVB) irradiation is thought to occur within a few minutes and is immediately decreased by the DNA repair system. null null null Objective null We evaluated the time course and differential effects of narrowband (NB-UVB) and broadband (BB-UVB) UVB on CPD formation. null null null Methods null We investigated CPD formation at various time-points in vivo, from 3 min to 72 h,...
#1Hanako Koguchi-Yoshioka (University of Tsukuba)H-Index: 5
#2Rei Watanabe (University of Tsukuba)H-Index: 11
Last. Hitoshi Shimano (University of Tsukuba)H-Index: 88
view all 12 authors...
Abstract null null Background null The efficacy of small molecule inhibitors for intracellular signal mediators varies among the individuals, and their mechanism of action is broad. A phosphodiesterase 4 inhibitor apremilast shows a dramatic effect on a certain proportion of psoriatic patients by modulating the cellular metabolism and regulating the production of pro-inflammatory molecules. However, it is unclear to which disease subtype this drug benefits. While psoriasis is a Th17-mediated dis...
#1Zhixing JiangH-Index: 3
#2Chen ChenH-Index: 2
view all 6 authors...
Top fields of study
Molecular biology
Atopic dermatitis
Cell biology