The association between Food allergy (FA), Vitamin D deficiency (VDD) and Vitamin D binding protein (VDBP) is of special interest (1). A previous study has shown that low serum Vitamin D levels were associated with food allergy, particularly amongst infants with specific VDBP gene polymorphisms (2). In addition, infants of Australian-born parents with inadequate vitamin D levels were more likely to be food allergic than were those with adequate vitamin D levels (3). In the United States, a signi...
AIM Adenovirus infections are exceedingly common in childhood. However, little is known of the clinical characteristics of children admitted with severe infection to the paediatric intensive care unit (PICU). METHODS Clinical data on children hospitalised with adenovirus infection between January 2005 and March 2020 were collected. We compared data between children hospitalised in the PICU and those who were not in a 1:2 ratio. RESULTS During the study period, 69 children with adenovirus infecti...
The risk of asthma is increased in children who have suffered from bronchiolitis in infancy and/or from wheezing associated with lower respiratory tract infection (LRTI) in early childhood. Asthma in mothers seems to be the most consistent risk factor for later asthma. Long-term follow-ups have suggested that the increased post-bronchiolitis asthma risk continues until adulthood. Bronchiolitis has usually been defined as the first episode of LRTI with expiratory difficulty.
AIM To ascertain and illustrate specific clinical dento-craniofacial characteristics associated with sleep-disordered breathing (SDB) in non-syndromic children. METHODS Narrative review of literature on SDB, dental occlusion and craniofacial morphology retrieved through online literature database search for these terms. The review focused on clinical examples and graphical illustrations in order to ascertain the association between dento-craniofacial characteristics and SDB. Only publications co...
Last. Hania Szajewska(Medical University of Warsaw)H-Index: 68
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Global prescriptions for proton pump inhibitors (PPIs) have been steadily increasing, particularly for infants. A recent study reported an increase from 137 per 10,000 eligible infants in 2009 to 450 in 2018.1 There are several well-documented indications for using PPIs for children with acid-related disorders, including erosive gastroesophageal reflux disease and eosinophilic esophagitis. They are also used as part of the eradiation therapy for Helicobacter pylori infections.2 However, PPIs are...
AIM Birth asphyxia can lead to organ dysfunction, varying from isolated biological acidosis to hypoxic-ischemic encephalopathy (HIE). Pathophysiology of moderate or severe HIE is now well known and guidelines exist regarding the care required in this situation. However, for newborns without moderate or severe HIE, no consensus is available. Our objective was to describe the immediate neonatal consequences and need for care of asphyxiated newborns without moderate or severe HIE. METHODS Multicent...
Last. Karin Collett(Haukeland University Hospital)H-Index: 11
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Aim null We evaluated the role of placental pathology in predicting adverse outcomes for neonates born extremely preterm (EPT) before 28 weeks of gestation. null Methods null This was a prospective observational study of 123 extremely preterm singletons born in a hospital in western Norway and the placentas were classified according to the Amsterdam criteria. The associations between histologic chorioamnionitis (HCA), by the presence or absence of a fetal inflammatory response (FIR+ or FIR-), ma...
AIM It is challenging to provide extremely low gestational age neonates (ELGANs) with adequate protein supply. This study aimed to investigate whether amino acid (AA) infusion in the umbilical artery catheter (UAC) in ELGANs is safe and enhances protein supply and growth. METHOD A before and after study including infants born <27 weeks, treated in Uppsala, Sweden, during 2004-2007, compared those receiving normal saline/10% dextrose in water with those receiving AA infusion in the UAC. Data were...
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