Muscle & Nerve
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#1Sara M. Takacs (IU: Indiana University)H-Index: 3
#2Amber Comer (IU: Indiana University)H-Index: 1
INTRODUCTION/AIMS Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive weakness. Survival is typically only a few years from symptom onset. The often-predictable disease course creates opportunities to complete advance care planning (ACP) forms. The Physician Orders for Life-Sustaining Treatment (POLST) is a broadly used ACP paradigm to communicate end-of-life wishes but has not been well-studied in the ALS population. METHODS In this retrospective cha...
#1Kristin M. Conway (UI: University of Iowa)H-Index: 8
#2Amber M. Gedlinske (UI: University of Iowa)
Last. Paul A. Romitti (UI: University of Iowa)H-Index: 58
view all 11 authors...
INTRODUCTION/AIMS Scoliosis is a common comorbidity among individuals diagnosed with a dystrophinopathy. We examined associations between clinical predictors and scoliosis in childhood-onset dystrophinopathy. METHODS The progression and treatment of scoliosis were obtained from data collected by the US population-based Muscular Dystrophy Surveillance, Tracking, and Research Network. Associations between loss of independent ambulation (LoA) and corticosteroid use and scoliosis outcomes (ages at o...
#1Lay Khoon LooH-Index: 1
#2Omar Salim (Royal Stoke University Hospital)
Last. Yusuf A. Rajabally (Aston University)H-Index: 28
view all 8 authors...
Introduction/aims null We aimed to determine whether specific severe acute respiratory syndrome coronavirus 2 (SARS-CoV2) vaccines may be associated with acute-onset polyradiculoneuropathy and if they may result in particular clinical presentations. null Methods null We retrospectively reviewed records of all persons presenting with acute-onset polyradiculoneuropathy from January 1, 2021, to June 30, 2021, admitted to two Neuroscience centers, of the West and North Midlands, United Kingdom. We c...
#1Rory M C Abrams (MSSM: Icahn School of Medicine at Mount Sinai)H-Index: 1
#2David M. Simpson (MSSM: Icahn School of Medicine at Mount Sinai)H-Index: 66
Last. Susan C. Shin (MSSM: Icahn School of Medicine at Mount Sinai)H-Index: 2
view all 6 authors...
INTRODUCTION/AIMS The development and persistence of neurological symptoms following severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is referred to as "long-haul" syndrome. We aimed to determine whether small fiber neuropathy (SFN) was associated with SARS-CoV-2 infection. METHODS We retrospectively studied the clinical features and outcomes of patients who were referred to us between May 2020 and May 2021 for painful paresthesia and numbness that developed during or after...
#1Pariwat Thaisetthawatkul (UNMC: University of Nebraska Medical Center)H-Index: 12
#1Kellen H Quigg (UM: University of Michigan–Ann Arbor)
#2Matthew W. Wilson (UM: University of Michigan–Ann Arbor)H-Index: 1
Last. Philip J. Choi (UM: University of Michigan–Ann Arbor)H-Index: 4
view all 3 authors...
Introduction/aims null Amyotrophic lateral sclerosis (ALS) is characterized by profound muscle weakness, including diaphragmatic weakness resulting in hypercapnic respiratory failure. While non-invasive ventilation (NIV) is usually initiated in the home, patients presenting with hypercapnic respiratory failure may be at high risk of adverse outcomes with delays in treatment. We aim to describe the clinical utility of transcutaneous CO2 (TCO2) to assess the need for inpatient initiation of NIV. n...
#1Lawrence R. Robinson (University of Toronto)H-Index: 42
#1Travis A. Prest (University of Pittsburgh)H-Index: 4
#2Tyler J. Meder (University of Pittsburgh)H-Index: 1
Last. Bryan N. Brown (University of Pittsburgh)H-Index: 30
view all 8 authors...
INTRODUCTION/AIMS While the peripheral nervous system has the inherent ability to recover following injury, results are often unsatisfactory, resulting in permanent functional deficits and disability. Therefore, methods that enhance regeneration are of significant interest. The present study investigates an injectable nerve-tissue-specific hydrogel as a biomaterial for nerve regeneration in a rat nerve crush model. METHODS Nerve-specific hydrogels were injected into the subepineurial space in bo...
#1Volkan Granit (UM: University of Miami)H-Index: 4
#2Anne-Laure Grignon (UM: University of Miami)
Last. Michael Benatar (UM: University of Miami)H-Index: 43
view all 12 authors...
The electronic health record (EHR) is designed principally to support the provision and documentation of clinical care, as well as billing and insurance claims. Broad implementation of the EHR, however, also yields an opportunity to use EHR data for other purposes, including research and quality improvement. Indeed, effective use of clinical data for research purposes has been a long-standing goal of physicians who provide care for patients with ALS, but the quality and completeness of clinical ...
#1Thapat Wannarong (CWRU: Case Western Reserve University)H-Index: 1
#2Thanat Chaikijurajai (MU: Mahidol University)H-Index: 3
Last. Patompong Ungprasert (Cleveland Clinic)H-Index: 30
view all 6 authors...
INTRODUCTION/AIMS Previous studies have shown inconsistent data on the relationship between statin use and polyneuropathy (PN). The current systematic review and meta-analyses were conducted to comprehensively investigate the risk of incident PN among statin-users compared with non-users by identifying all available studies and summarizing their results. METHODS A systematic review was conducted from MEDLINE and EMBASE databases from inception to October 31, 2020. We included cohort and case-con...
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