Brain Structure & Function
Papers 2136
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#1Nicola Palomero-Gallagher (Forschungszentrum Jülich)H-Index: 47
#2Katrin Amunts (Forschungszentrum Jülich)H-Index: 95
Emotions are valenced mental responses and associated physiological reactions that occur spontaneously and automatically in response to internal or external stimuli, and can influence our behavior, and can themselves be modulated to a certain degree voluntarily or by external stimuli. They are subserved by large-scale integrated neuronal networks with epicenters in the amygdala and the hippocampus, and which overlap in the anterior cingulate cortex. Although emotion processing is accepted as bei...
#1Mauro Chivite (University of Vigo)H-Index: 4
#2Esther Leal (CSIC: Spanish National Research Council)H-Index: 9
Last. José Miguel Cerdá-Reverter (CSIC: Spanish National Research Council)H-Index: 35
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Serotonin (5-HT) is one of the principal neurotransmitters in the nervous system of vertebrates. It is initially synthesized by hydroxylation of tryptophan (Trp) by means of tryptophan hydroxylase or TPH which is the rate-limiting enzyme in the production of 5-HT. In most vertebrates, there are two isoforms of TPH present, TPH1 and TPH2, which exhibit different catalytic or substrate specificity as well as different expression domains. Studies carried out in mammals show that only tph2 is expres...
#1Asmae Lguensat (CNRS: Centre national de la recherche scientifique)H-Index: 1
#2Christian Montanari (LSU: Louisiana State University)H-Index: 2
Last. René Garcia (CNRS: Centre national de la recherche scientifique)H-Index: 19
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Pre- and post-trauma drug use can interfere with recovery from post-traumatic stress disorder (PTSD). However, the biological underpinnings of this interference are poorly understood. Here we examined the effect of pre-fear conditioning cocaine self-administration on PTSD-like symptoms in male rats, and defined impairment of fear extinction as difficulty to recover from PTSD. We also examined cell density changes in brain regions suspected of being involved in resistance to PTSD recovery. Before...
#1Ümit S. Mayadali (LMU: Ludwig Maximilian University of Munich)H-Index: 1
#2Jérome Fleuriet (UW: University of Washington)H-Index: 9
Last. Anja K. E. Horn (LMU: Ludwig Maximilian University of Munich)H-Index: 32
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Extraocular motoneurons initiate dynamically different eye movements, including saccades, smooth pursuit and vestibulo-ocular reflexes. These motoneurons subdivide into two main types based on the structure of the neuro-muscular interface: motoneurons of singly-innervated (SIF), and motoneurons of multiply-innervated muscle fibers (MIF). SIF motoneurons are thought to provoke strong and brief/fast muscle contractions, whereas MIF motoneurons initiate prolonged, slow contractions. While relevant ...
#1John Shallcross (UF: University of Florida)H-Index: 4
#2Lizhen Wu (UF: University of Florida)H-Index: 4
Last. Marek Schwendt (UF: University of Florida)H-Index: 19
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Post-traumatic stress disorder (PTSD) develops in a subset of individuals exposed to a trauma with core features being increased anxiety and impaired fear extinction. To model the heterogeneity of PTSD behavioral responses, we exposed male Sprague–Dawley rats to predator scent stress once for 10 min and then assessed anxiety-like behavior 7 days later using the elevated plus maze and acoustic startle response. Rats displaying anxiety-like behavior in both tasks were classified as stress Suscepti...
#1Ellie A. Bucher (UTAS: University of Tasmania)
#2Jessica M. Collins (UTAS: University of Tasmania)H-Index: 4
Last. Matthew T. K. Kirkcaldie (UTAS: University of Tasmania)H-Index: 1
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The calcium binding protein parvalbumin is expressed in interneurons of two main morphologies, the basket and chandelier cells, which target perisomatic domains on principal cells and are extensively interconnected in laminar networks by synapses and gap junctions. Beyond its utility as a convenient cellular marker, parvalbumin is an unambiguous identifier of the key role that these interneurons play in the fundamental functions of the cortex. They provide a temporal framework for principal cell...
#1Tiantian Liu (BIT: Beijing Institute of Technology)H-Index: 7
#2Yan Yan (BIT: Beijing Institute of Technology)H-Index: 1
Last. Tianyi Yan (BIT: Beijing Institute of Technology)H-Index: 14
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Parkinson’s disease (PD) can be considered as the dysfunction in segregation and integration of large-scale structural networks in the late stage of disease progression. However, the altered patterns in the early stage have not been extensively investigated, especially the altered structural rich-club patterns, which is proved powerful to detect the altered patterns of structural networks in Alzheimer’s disease and schizophrenia. To this end, we investigated the rich-club organization of the str...
#1Robin Gerrits (UGent: Ghent University)H-Index: 6
#2Helena Verhelst (UGent: Ghent University)H-Index: 7
Last. Guy Vingerhoets (UGent: Ghent University)H-Index: 49
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Functional and anatomical hemispheric asymmetries abound in the neural language system, yet the relationship between them remains elusive. One attractive proposal is that structural interhemispheric differences reflect or even drive functional language laterality. However, studies on structure–function couplings either find that left and right language dominant individuals display similar leftward structural asymmetry or yield inconsistent results. The current study aimed to replicate and extend...
#1Franco Cauda (UNITO: University of Turin)H-Index: 32
#2Andrea Nani (UNITO: University of Turin)H-Index: 13
Last. Tommaso Costa (UNITO: University of Turin)H-Index: 22
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Asymmetries in gray matter alterations raise important issues regarding the pathological co-alteration between hemispheres. Since homotopic areas are the most functionally connected sites between hemispheres and gray matter co-alterations depend on connectivity patterns, it is likely that this relationship might be mirrored in homologous interhemispheric co-altered areas. To explore this issue, we analyzed data of patients with Alzheimer's disease, schizophrenia, bipolar disorder and depressive ...
#1Hidehiko Komatsu (Tamagawa University)H-Index: 36
#2Akiko NishioH-Index: 2
Last. Naokazu GodaH-Index: 17
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The inferior temporal (IT) cortex of the macaque monkey plays a pivotal role in the visual recognition of objects. In the IT cortex, a feature-selective network formed by connecting subregions specialized for common visual features seems to be a basic strategy for processing biologically important visual features. Gloss perception plays an important role in the judgment of materials and conditions of objects and is a biologically significant visual function. In the present study, we attempted to...
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