Japanese Journal of Ophthalmology
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#1Aya Takahashi (Tokyo Dental College)H-Index: 1
#2Takefumi Yamaguchi (Tokyo Dental College)H-Index: 22
Last. Jun Shimazaki (Tokyo Dental College)H-Index: 70
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PURPOSE To characterize trends in procedures, and indications for corneal transplantation over 27 years in a single referral center in Japan. STUDY DESIGN Retrospective study. METHODS Data from a consecutive series of corneal transplant surgery cases performed from 1991 to 2017at Ichikawa General Hospital were collected. The surgical procedures, indications, and causes of corneal endothelial dysfunction were evaluated. RESULTS Among 6,025 transplantations, a total of 3,991 cases underwent penetr...
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#1Asuka Takeyama (Teikyo University)H-Index: 6
#2Yutaka Imamura (Teikyo University)H-Index: 24
Last. Masahiro Ishida (Toho University)H-Index: 6
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Purpose null Vital dyes are frequently used to visualize the internal limiting membrane (ILM) of the neuroretina. This study evaluated and compared the microstructure of the inner retina and visual function with and without brilliant blue G (BBG) staining for ILM peeling during idiopathic epiretinal membrane (ERM) surgery. null Study design null Retrospective, consecutive, interventional case series. null Methods null Fifty-five patients (55 eyes) with ERM underwent ILM peeling without dyes (non...
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#1Akihiko Umazume (TMU: Tokyo Medical University)H-Index: 5
#2Nobuyuki OhguroH-Index: 24
Last. Hiroshi Goto (TMU: Tokyo Medical University)H-Index: 28
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To estimate the nationwide, longitudinal prevalence and incidence rates and assess treatment patterns of non-infectious uveitis (NIU) in Japan. A retrospective study. Health insurance claims’ data of patients with NIU were extracted from the Japan Medical Data Center (JMDC) database and analyzed descriptively (data extraction period, January 2011 to May 2017). Behcet’s disease (BD), Vogt-Koyanagi-Harada (VKH) disease, and sarcoidosis were selected as the primary diseases of NIU. From 2011 to 201...
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#1Hiroshi Goto (TMU: Tokyo Medical University)H-Index: 28
#2Shunichiro Ueda (TMU: Tokyo Medical University)H-Index: 8
Last. Atsushi AzumiH-Index: 17
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PURPOSE The aim of this study was to elucidate the clinical features and symptoms of IgG4-related ophthalmic disease (IgG4-ROD). STUDY DESIGN Retrospective, multicenter study. METHODS The medical charts of 378 patients with IgG4-ROD diagnosed at 9 hospitals in Japan were reviewed. The demographic profiles, clinical findings, and ocular symptoms of the patients were analyzed. RESULTS On the basis of the diagnostic criteria for IgG4-ROD, the diagnosis was definite in 261 patients (69%), probable i...
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#1Frank H. P. Lai (Caritas Medical Centre)H-Index: 8
#2Rose P. S. Chan (Caritas Medical Centre)
Last. Can Y. F. Yuen (Caritas Medical Centre)H-Index: 10
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PURPOSE To compare two-year treatment outcomes of subthreshold micropulse (577 nm) laser and aflibercept for diabetic macular edema (DME). STUDY DESIGN Retrospective case-control study. METHODS A total 164 eyes in 164 DME patients treated with either micropulse laser (86 eyes) or intravitreal aflibercept monotherapy (78 eyes) were recruited. Main outcome measures included at least five Early Treatment Diabetic Retinopathy Study (ETDRS) letters' improvement from baseline at 6, 12 and 24 months. R...
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#1Shuhei Kimura (Okayama University)H-Index: 13
#2Yuki Morizane (Okayama University)H-Index: 13
Last. Fumio Shiraga (Okayama University)H-Index: 16
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PURPOSE To evaluate the cytotoxic effects of alteplase, a recombinant tissue plasminogen activator, and its additives on human retinal pigment epithelial (hRPE) cells. STUDY DESIGN Laboratory study. METHODS We evaluated the cytotoxic effects of alteplase on human fetal RPE (hfRPE) cells, human induced pluripotent stem cell-derived RPE (hiPS-RPE), and ARPE-19 cells, as well as the cytotoxic effects of L-arginine and polysorbate 80, two additives of alteplase, on hfRPE cells. The effects of altepl...
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#1Nurettin Bayram (University of Health Science)H-Index: 1
#2Cemal Ozsaygılı (University of Health Science)H-Index: 1
Last. İbrahim Özcan (University of Health Science)H-Index: 2
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PURPOSE: To present the different clinical manifestations of rhino-orbital mucormycosis (ROM) co-infection in severe COVID-19 patients. STUDY DESIGN: Prospective observational clinical study METHODS: Among 32,814 patients hospitalized with the diagnosis of COVID-19 between March 2020 and December 2020 in our center, eleven microbiologically confirmed ROM co-infection cases in severe COVID-19 patients were evaluated. RESULTS: There were nine men and two women with a mean age of 73.1 ± 7.7 years. ...
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#1Tomoko Goto (Ehime University)H-Index: 11
#2Atsushi Shiraishi (Ehime University)H-Index: 23
Last. Shigeru KinoshitaH-Index: 101
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PURPOSE This study investigated the safety and efficacy of orthokeratology in myopic children in Japan. STUDY DESIGN Prospective clinical trial. METHODS This study enrolled myopic children aged 6-16 years with a spherical equivalent of -1.00 D to -4.00 D and astigmatism of -1.5 D or lower, whose parents could manage contact lens use and could provide written informed consent. The children were treated with orthokeratology lenses (BREATH-O CORRECT R, Universal View Co., Ltd.) for 3 years. Slit-la...
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#1Hitomi Shibata (Akita University)H-Index: 2
#2Yu Sawada (Akita University)H-Index: 9
Last. Takeshi Iwase (Akita University)H-Index: 1
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PURPOSE To investigate peripapillary choroidal thickness (PPCT) in normal Japanese subjects by using spectral-domain optical coherence tomography (SD-OCT) with enhanced depth imaging (EDI) technique and evaluate its association with ocular and systemic factors. STUDY DESIGN Cross-sectional study. METHODS This study included 85 eyes of 85 normal Japanese subjects. Normal subjects were defined as those without retinal and optic nerve disorders of any kind. The PPCT was measured at the location of ...
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#1Masanori Nakazawa (Kadai: Kagoshima University)H-Index: 1
#2Hitoshi Ishikawa (Kitasato University)H-Index: 15
Last. Taiji Sakamoto (Kadai: Kagoshima University)H-Index: 60
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Optic neuritis is an ocular disorder whose pathogenesis has not been fully determined, although autoimmune mechanisms have been suggested to be involved in its development. In recent years, anti-aquaporin-4 antibody (AQP4-Ab) and anti-myelin oligodendrocyte glycoprotein antibody (MOG-Ab) have been shown to play major roles in the development of optic neuritis. Because these two antibodies target different tissues, optic neuritis can be classified by the type of antibody. AQP4-Ab-positive optic n...
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