Clinical Nephrology
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#1Ryo HazueH-Index: 4
#2Toshiharu UenoH-Index: 12
Last. Yoshifumi UbaraH-Index: 25
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A 33-year-old Japanese man with no significant past medical history was admitted to our hospital for evaluation of weight gain and pitting edema. A laboratory test confirmed nephrotic-range proteinuria. Renal biopsy showed subepithelial deposits, and membranous nephropathy (MN) was diagnosed. Closer examination clarified an active syphilis infection. After renal biopsy, we prescribed amoxicillin for 8 weeks to treat the syphilis infection. Three weeks later, the patient's proteinuria dramaticall...
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#1Arzu OzdemirH-Index: 1
#2Sibel Yucel KocakH-Index: 1
Last. Murvet YilmazH-Index: 9
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AIM The prevalence of kidney disease and the number of renal biopsies performed in the elderly are increasing with aging of the population. We aimed to analyze the clinicopathological findings of kidney diseases in the elderly (≥ 65 years), in comparison with their younger counterparts (aged 16 - 64 years). MATERIALS AND METHODS The data at the time of renal biopsy were obtained by reviewing medical records and the biopsy reports of the patients retrospectively. The data at the time of renal bio...
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AIM Autosomal dominant inheritance of Alport syndrome (AS) is very rare, and only a few unrelated families have been found with COL4A3 or COL4A4 gene mutations. Therefore, we aimed to explore the COL4A4 gene mutation spectrum in autosomal recessive Alport syndrome (ARAS). MATERIALS AND METHODS Blood samples of the proband and his parents were sent to the Institute of Rare Diseases at the West China Hospital of Sichuan University for genetic testing. The analyzed genes were COL4A3-5. The chip cap...
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#2Hyung Ah JoH-Index: 7
Last. Sang Youb HanH-Index: 21
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INTRODUCTION The incidence of fractures is much higher in patients with chronic kidney disease, especially those on hemodialysis (HD). Denosumab is known to treat osteoporosis. However, no exact guideline exists for treatment with denosumab in patients, especially those with diabetes. This study analyzed the effect of denosumab in HD patients with or without diabetes. MATERIALS AND METHODS Dual-energy X-ray absorptiometry was performed in 89 HD patients: 42 were diagnosed with osteoporosis. 33 p...
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OBJECTIVE This paper was written to systematically review and meta-analyze the evidence on the efficacy of lanthanum carbonate (LC) and calcium carbonate (CC) and the risk of cardiovascular calcification on hemodialysis (HD) patients. MATERIALS AND METHODS The Cochrane library, PubMed, Web of Science, Chinese journal full-text database (CNKI), WANGFANG DATA, and Sino Med were searched between January 1946 and December 2020. The literature with respect to the randomized controlled clinical trial ...
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#2Jung Pyo LeeH-Index: 21
Last. Chun Soo LimH-Index: 24
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Iron replacement therapy is necessary for anemia treatment in patients with advanced chronic kidney disease. Intravenous (IV) iron therapy is an efficient method for iron replacement. However, there are concerns regarding its considerable side effects, including increased risks of infection or major adverse cardiovascular events (MACE). This is a longitudinal study from a multicenter prospective cohort study conducted in the Korean end-stage renal disease population. All-cause mortality, death d...
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#1Jana UhlinovaH-Index: 2
#2Anne KuudebergH-Index: 4
Last. Mai Ots-RosenbergH-Index: 8
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AIM The aim of this study was to compare vascular calcification (VC) in obese and non-obese chronic kidney disease (CKD) patients, using three methods for measuring VC. MATERIALS AND METHODS The study included 168 consecutive patients with CKD. Patients were divided into two groups by body mass index (BMI) - group 1 (BMI ≥ 30 kg/m2) and group 2 (BMI < 30 kg/m2), and according to estimated glomerular filtration rate (eGFR) - subgroup A (eGFR ≥ 45 mL/min/1.73m2) and subgroup B (eGFR < 45 mL/min/1....
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#1Markus MeierH-Index: 11
Last. Stefan JäckleH-Index: 2
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BACKGROUND The prevalence of chronic kidney disease (CKD) requiring dialysis therapy is increasing globally. Survival and mortality data of these patients in Germany are fragmentary since the nationwide registry was terminated in 2006. OBJECTIVE The objective of this study was to analyze the survival, causes of death, and co-morbidities of dialysis patients in a German population cohort as well as to assess the factors influencing mortality in these patients. MATERIALS AND METHODS We included ad...
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Top fields of study
Endocrinology
Surgery
Hemodialysis
Kidney disease
Diabetes mellitus
Medicine